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1.
Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping.
Neoplasia;
23(2): 210-221, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33385970
2.
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-derived Xenografts.
Mol Cancer Ther;
19(10): 2079-2088, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32788205
3.
Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs).
ACS Med Chem Lett;
10(8): 1193-1197, 2019 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31413805
4.
The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models.
Haematologica;
104(8): 1633-1639, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30733273
5.
IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML.
Mol Cancer Ther;
17(6): 1271-1279, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29588393
6.
A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody-Drug Conjugates (ADCs).
Mol Cancer Ther;
17(3): 650-660, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29440292
7.
The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models.
Neoplasia;
19(9): 661-671, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28753442
8.
A New Triglycyl Peptide Linker for Antibody-Drug Conjugates (ADCs) with Improved Targeted Killing of Cancer Cells.
Mol Cancer Ther;
15(6): 1311-20, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27197308
9.
Evaluation of Targets for Maytansinoid ADC Therapy Using a Novel Radiochemical Assay.
Pharm Res;
32(11): 3593-603, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25630819
10.
A novel anti-CD37 antibody-drug conjugate with multiple anti-tumor mechanisms for the treatment of B-cell malignancies.
Blood;
122(20): 3500-10, 2013 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24002446
11.
Disulfide-linked antibody-maytansinoid conjugates: optimization of in vivo activity by varying the steric hindrance at carbon atoms adjacent to the disulfide linkage.
Bioconjug Chem;
22(4): 717-27, 2011 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-21425776
12.
Antibody-maytansinoid conjugates designed to bypass multidrug resistance.
Cancer Res;
70(6): 2528-37, 2010 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20197459
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