Eating through time: Understanding dietary practices across late prehistory in the northeastern Iberian Peninsula.

OBJECTIVE: This study seeks to contribute to the current understanding of dietary variation in the late Prehistory of the northeastern Iberian Peninsula by examining buccal dental microwear patterns alongside archeological data from the same populations. MATERIALS AND METHODS: Teeth from 84 adult individuals from eight distinct samples spanning the Middle-Late Neolithic to the Middle Bronze Age (Cova de l'Avi, Cova de Can Sadurní, Cova de la Guineu, Cova Foradada, Cova del Trader, Roc de les Orenetes, Cova del Gegant, Cova dels Galls Carboners) were analyzed using optical microscopy to examine buccal dental microwear patterns. RESULTS: The analysis did not reveal clear chronological contrasts in the dietary habits of these samples. Nevertheless, significant differences emerged among the samples, leading to their classification into two distinct sets based on the abrasiveness of the diet informed by the microwear patterns. These findings offer similarities and differences among samples in the Iberian Peninsula, shedding light on the diverse lifestyles of these individuals. DISCUSSION: Integrating our new results with other available proxies points to a multifaceted specialization in dietary patterns among these samples, influenced by factors such as habitat, resource selection, and available technology. By contextualizing the results within the broader context of the Iberian Peninsula, this research discerns shared characteristics and distinctive adaptations in the dietary practices and subsistence strategies of these groups. Ultimately, this study contributes to a deeper understanding of the intricate interplay between culture and environment in shaping human diets throughout late Prehistory.

Lagged Effect of Parental Warmth on Child-to-Parent Violence through Moral Disengagement Strategies.

Empirical evidence supports the simultaneous relationship between parental warmth and child-to-parent violence (CPV). However, no studies analyze the lagged effects of perceived parental warmth and the potential impact of cognitive mechanisms legitimizing immoral behavior on this relationship. This study aimed to examine the mediating role of moral disengagement strategies (reconstruction of immoral behavior, obscuring personal responsibility, misrepresenting injurious consequences, and blaming the victim) in the relationship between the perceived paternal and maternal warmth dimensions (warmth-communication and criticism-rejection) during childhood and CPV towards the father and mother. The sample included 2122 Spanish adolescents (57.7% female) aged 13 to 18 years. The Child-to-Parent Violence Questionnaire (CPV-Q), the Mechanisms of Moral Disengagement Scale (MMDS-S), and the Warmth Scale were used as assessment instruments. The results indicate that paternal and maternal warmth-communication is negatively associated with CPV, whereas paternal and maternal criticism-rejection and moral disengagement strategies are positively related to CPV. The mediation models show that the reconstruction of immoral behavior plays a crucial mediation role in the relationship between paternal and maternal warmth-communication and CPV as well as in the relationship between maternal criticism-rejection and CPV. The results emphasize the necessity of early prevention programs for parents promoting positive parenting practices, including parental warmth, to foster children's adaptive socio-cognitive development. In addition, addressing moral disengagement in adolescents could help prevent or stop a pattern of violent behavior toward parents.

Characterization of the Electrophysiological Characteristics of Chronic Atrial Fibrillation for Efficient Simulations.

Atrial biophysical simulations have the potential to enhance outcomes by enabling the simulation of pharmacological and ablative strategies. However, the high computational times associated with such simulations render them unsuitable for diagnostic purposes. To address this challenge, discrete models such as cellular automata (CA) have been developed, which consider a finite number of states, thus significantly reducing computational times. Yet, there is a pressing need to determine whether CA can replicate pathological simulations with accuracy. The analysis of simulations under different degrees of electrical remodeling shows an expected increase of Action Potential Duration (APD) with the previous Diastolic Interval (DI) interval, indicating short-term memory of atrial cardiomyocytes: shorter APD0 provoked shorter APD+1, and previous DI has a similar effect on APD+1. Independent prediction using both APD0 and DI was found to provide a far better estimation of APD+1 values, compared to relying on DI alone (p<<0.01). Finally, the CA models were able to replicate reentrant patterns and cycle lengths of different states of atrial remodeling with a high degree of accuracy when compared to biophysical simulations. Overall, the use of atrial CA with short-term memory allows accurate reproduction of arrhythmic behavior in pathological tissue within a clinically relevant timeframe.Clinical Relevance- Discrete electrophysiological models simulate pathological self-sustained arrhythmias in diagnostic times.

Assessment of Risk for Ventricular Tachycardia based on Extensive Electrophysiology Simulations.

Patients that have suffered a myocardial infarction are at high risk of developing ventricular tachycardia. Patient stratification is often determined by characterization of the underlying myocardial substrate by cardiac imaging methods. In this study, we show that computer modeling of cardiac electrophysiology based on personalized fast 3D simulations can help to assess patient risk to arrhythmia. We perform a large simulation study on 21 patient digital twins and reproduce successfully the clinical outcomes. In addition, we provide the sites which are prone to sustain ventricular tachycardias, i.e, onset sites around the scar region, and validate if they colocalize with exit sites from slow conduction channels.Clinical relevance- Fast electrophysiological simulations can provide advanced patient stratification indices and predict arrhythmic susceptibility to suffer from ventricular tachycardia in patients that have suffered a myocardial infarction.

Instruments of Child-to-Parent Violence: Systematic Review and Meta-Analysis.

This systematic review and reliability generalization meta-analysis synthesized psychometric literature on instrumentation assessing child-to-parent violence published through September 2023 across four databases. In the screening, we identified studies reporting Cronbach's alpha internal consistency estimates for the child-to-parent violence scales. The eligible reliability coefficients ranged from 0.610 to 0.930, mostly exceeding the minimum threshold of 0.700. Random-effects models calculated pooled Cronbach's alphas separately for global, father-specific, and mother-specific subscales. The results demonstrated cumulative values of 0.83 (global: standard error = 0.0129), 0.800 (fathers: standard error = 0.0203), and 0.81 (mothers: standard error = 0.0179), denoting largely adequate reliability. However, significant between-study heterogeneity was observed. While the mean alpha levels seem acceptable for most tools, substantial variability coupled with the possibility of some studies violating reliability assumptions indicates that a conservative interpretation is warranted. Ongoing scale refinement and additional psychometric evaluations will strengthen the rigor methodology in this developing research domain. However, these results should be interpreted with caution, as there is a high level of heterogeneity, and it is possible that some studies have not verified the assumptions underlying Cronbach's alpha.

[Epilepsy and inequality: demographic description and analysis of the difficulty in accessing advanced resources in a population in a small health area]. / Epilepsia y desigualdad: descripción demográfica y análisis de la dificultad para el acceso a recursos avanzados en una población de un área de salud pequeña.

INTRODUCTION: Epilepsy is a very common neurological disease with high morbidity and mortality. Drug-resistant epilepsy (DRE) poses a major therapeutic challenge, even for experts in the field. Despite this, access to advanced resources for this type of patient remains difficult and unequal. The aim of this study is to analyse inequality in a population belonging to a first level hospital. PATIENTS AND METHODS: An analytical observational cross-sectional study was conducted on epileptic patients attending neurology consultations in Area IX of the Murcian Health Service. Demographic, clinical, therapeutic, prognostic and equity variables are described, and significant differences between different subgroups are analysed. RESULTS: The study included 68 patients with a mean age of 42.93 years. Focal epilepsy was the main type (64.7%), and the most commonly used drugs were levetiracetam (33.8%), valproic acid (27.9%) and lamotrigine (22.1%). DRE occurred in 18 patients (26.5% of the total) and only four were under active follow-up in an epilepsy unit, meaning that 71% did not have access to a necessary resource (advanced therapeutic gap). CONCLUSIONS: This study demonstrates that epilepsy inequality continues to be a problem, especially in certain geographical areas, with a lack of access to advanced care for patients who need it most. The solution can be achieved by increasing human and material resources to improve overall patient care, thus strengthening both referral hospitals and epilepsy units.

TITLE: Epilepsia y desigualdad: descripción demográfica y análisis de la dificultad para el acceso a recursos avanzados en una población de un área de salud pequeña.Introducción. La epilepsia es una enfermedad neurológica muy frecuente que implica una elevada morbimortalidad. La epilepsia farmacorresistente (EFR) supone un desafío terapéutico superior, incluso para expertos en la materia. A pesar de ello, el acceso a recursos avanzados para este tipo de pacientes continúa siendo dificultoso y desigual. El objetivo de este estudio es analizar la desigualdad en una población perteneciente a un hospital de primer nivel. Pacientes y métodos. Se llevó a cabo un estudio transversal observacional analítico con pacientes epilépticos que acuden a consultas de neurología del área IX del Servicio Murciano de Salud. Se describen variables demográficas, clínicas, terapéuticas, pronósticas y de equidad, y se analizan diferencias significativas entre distintos subgrupos. Resultados. En el estudio se incluyó a 68 pacientes con una media de edad de 42,93 años. El tipo de epilepsia principal fue la focal (64,7%), y los fármacos más usados fueron el levetiracetam (33,8%), el ácido valproico (27,9%) y la lamotrigina (22,1%). La EFR se dio en 18 pacientes (el 26,5% del total) y sólo cuatro se encontraban en seguimiento activo en una unidad de epilepsia, lo que implica que el 71% no accedía a un recurso necesario (advanced therapeutic gap). Conclusiones. Este estudio demuestra que la desigualdad en la epilepsia continúa siendo un problema, especialmente en ciertas áreas geográficas, con una falta de acceso a atención avanzada en pacientes que más lo necesitan. La solución puede conseguirse aumentando recursos humanos y materiales que mejoren la atención global del paciente, reforzando así tanto los hospitales de referencia como las unidades de epilepsia.

Relationship between child-to-parent violence and cumulative childhood adversity: the mediating role of parental attachment, resilience, and emotional intelligence.

Introduction: Recent research on aggressor profiles in child-to-parent violence (CPV) seems to provide promising results. However, this phenomenon has been poorly addressed in the adverse childhood experiences (ACEs) framework. This study aimed to explore the frequency of different types of ACEs and cumulative ACEs in adolescents who exert CPV, to analyze the differences between aggressors with different levels of cumulative ACEs in parental attachment, resilience, and emotional intelligence, and to evaluate the associations between these variables, as well as a possible mediational model. Methods: A total of 3,142 Spanish adolescents (50.7% girls) aged between 12 and 18 years from educational centers participated. Results: Adolescents who exerted CPV presented higher rates of ACEs both independently and cumulatively than those without CPV. Aggressors with cumulative ACEs (88%) in general presented more insecure parental attachment, lower resilience, and lower emotional intelligence than those without cumulative ACEs, and, in turn, aggressors with high levels of cumulative ACEs than those with low levels of cumulative ACEs. Significant associations were identified between CPV, ACEs, insecure parental attachment, resilience, and emotional intelligence. The mediation model suggested that ACEs are related to CPV through preoccupied and traumatized parental attachment and also through low levels of emotional intelligence. Discussion: The findings provide a better understanding of CPV from the perspective of ACEs, especially of those cases that involve an accumulation of adverse experiences during childhood, and suggest greater professional attention to these cases with the design of specialized CPV intervention programs.

Pathologist-initiated reflex testing for biomarkers in non-small-cell lung cancer: expert consensus on the rationale and considerations for implementation.

Biomarker tests in lung cancer have been traditionally ordered by the treating oncologist upon confirmation of an appropriate pathological diagnosis. The delay this introduces prolongs yet further what is already a complex, multi-stage, pre-treatment pathway and delays the start of first-line systemic treatment, which is crucially informed by the results of such analysis. Reflex testing, in which the responsibility for testing for an agreed range of biomarkers lies with the pathologist, has been shown to standardise and expedite the process. Twelve experts discussed the rationale and considerations for implementing reflex testing as standard clinical practice.

Exposure to Violence during Childhood and Child-to-Parent Violence: The Mediating Role of Moral Disengagement.

This study examines the influence of exposure to family violence during childhood on child-to-parent violence (CPV) through moral disengagement. The sample included 1868 Spanish adolescents aged between 13 and 18 years (57.9% female, Mage = 14.94, SD = 1.37). Participants completed the Child-to-Parent Violence Questionnaire, the Mechanisms of Moral Disengagement Scale, and the Exposure to Violence Scale during childhood. Results showed that exposure to family violence during childhood (vicarious and direct violence) contribute independently and positively to CPV. Moreover, the relationship between vicarious and direct exposure to family violence and CPV is mediated by moral disengagement. The structural model was replicated for both CPV towards the father and CPV towards the mother. The results highlight the importance of early exposure to family violence and moral disengagement in violent behavior towards parents. It is necessary to stage an early intervention with children who have been exposed to family violence in order to prevent an intergenerational transmission of violent behaviors.

Risk Factors in Specialists and Generalists of Child-to-Parent Violence: Gender Differences and Predictors of Reactive and Proactive Reasons.

Recent research on child-to-parent violence (CPV) is advancing in the analysis of the specialist profile (aggressors who show only CPV) and the generalist profile (aggressors who show peer violence in addition to CPV). However, although differences have been found between girls and boys in the risk factors for CPV, there are no studies that analyze these differences according to the type of aggressor. Likewise, the importance of identifying the factors that differentially predict reactive and proactive CPV has been noted but has not been examined in different types of aggressors. The aims of this study were to examine gender differences in CPV patterns, emotional intelligence, parental victimization, and parental permissiveness and to analyze whether these variables predict reactive and proactive CPV, both according to aggressor type. A total of 1559 Spanish CPV aggressors (54.6% females) aged between 12 and 18 years from educational centers participated in the study (22.4% exercised only CPV (specialists) and 77.6% exercised peer violence in addition to CPV (generalists)). In general, no differences were found between girls and boys in the specialist profile, but differences were found in the generalist profile. Specifically, generalist girls exercised more psychological and control/domain violence toward mothers, while boys exercised more physical violence toward fathers and had more parental permissiveness. In specialists, parental victimization predicted reactive CPV, while parental permissiveness predicted proactive CPV. In contrast, in generalists, both parental victimization and parental permissiveness predicted both reactive and proactive CPV. Low emotional regulation was a significant predictor in both cases. This study identifies differences among girls and boys in CPV risk factors and among variables that predict reactive and proactive CPV and that these results differ between specialist and generalist aggressors. Implications for research and professional practice are discussed, highlighting the need to design and implement prevention and intervention programs specialized in the type of aggressor, paying special attention to gender differences and to the factors that motivate one or the other type of CPV.

How kidney clock works: circadian pattern of eGFR based on a population data group.

A circadian regulation of renal function it has been described in the last few years. An intradaily variation in glomerular filtration rate (eGFR) has also been discovered at the individual level. The aim of this study was to check if there exists a circadian pattern of eGFR at population data group level and to compare the population results with those described at individual level. We have studied a total of 446,441 samples analysed in the emergency laboratories of two Spanish hospitals between January 2015 and December 2019. We selected all the records of eGFR values between 60 and 140 mL/min/1.73 m2 using CKD-EPI formula from patients between 18 and 85 years. The intradaily intrinsic eGFR pattern was computed using the extraction time of day in four nested mixed linear and sinusoidal regression models. All models showed an intradaily eGFR pattern, but the estimated model coefficients differed depending on whether age was included. The inclusion of age improved the performance of the model. In this model, the acrophase occurred at 7:46 h. We describe the distribution of eGFR values depending on the time in two different populations. This distribution is adjusted to a circadian rhythm that behaves similarly to the individual rhythm. This pattern is similar in each of the years studied from each hospital as well as between both hospitals. The results found suggest the incorporation of the concept of "population circadian rhythm" into the scientific world.

Assessment of single-nucleotide variant discovery protocols in RNA-seq data from human cells exposed to mycotoxins.

Food and feed contamination by nonlegislated mycotoxins beauvericin (BEA) and enniatin B (ENB) is a worldwide health concern in the present. The principal objective of this work is to assess some of the existing protocols to discover the single nucleotide variants (SNVs) in transcriptomic data obtained by RNA-seq from Jurkat cells in vitro samples individually exposed to BEA and ENB at three concentration levels (1.5, 3 and 5 µM). Moreover, previous transcriptomic results will be compared with new findings obtained using a different protocol. SNVs rs201003509 in BEA exposed cells and the rs36045790 in ENB were found in the differentially expressed genes in all doses compared to controls by means of the Genome Analysis Toolkit (GATK) Best Practices workflow. SNV-RNA-seq complementary pipeline did not show any SNV. Concerning gene expression, discrepant results were found for 1.5 µM BEA exposed cells compared with previous findings. However, 354 overlapped differentially expressed genes (DEGs) were identified in the three ENB concentrations used, with 147 matches with respect to the 245 DEGs found in the previous results. In conclusion, the two discovery SNVs protocols based on variant calling from RNA-seq used in this work displayed very different results and there were SNVs found manually not identified by any pipeline. Additionally, the new gene expression analysis reported comparable but non identical DEGs to the previous transcriptomic results obtained from these RNA-seq data.

Study of the fatigue delamination behaviour of adhesive joints in carbon fibre reinforced epoxy composites, influence of the period of exposure to saline environment.

This work analyses the fatigue delamination and fracture stress behaviour under mode I of adhesive joints made on an epoxy matrix composite material with unidirectional carbon fibre reinforcement and a commercial epoxy-based adhesive. DCB type tests (for mode I) were used with the aim to quantify the influence of the period of exposure to a degradation process in a salt spray chamber, to which the tested samples were subjected, on their fatigue behaviour. For this purpose and after a previous static characterisation of the material in which the critical values of the energy release rate for different exposure periods were determined, the levels of the energy release rate to be applied in the fatigue tests and the exposure periods to be considered (no exposure, exposure during one week and twelve weeks) and a ratio of fatigue stress levels of R = Gmin/Gmax = 0.1 were defined. From this experimental data, the G-N fatigue initiation curves and the G-da/dN growth curves were obtained. The experimental data obtained, in the fatigue initiation phase of the delamination process, have been treated by means of a probabilistic model based on a Weibull distribution, the application of models of these characteristics has allowed a better interpretation of the experimental results obtained. The most relevant result of the work is that, in general, the fatigue limits obtained for the adhesive joint, under mode I fracture, when subjected to a degradation process in a saline environment, do not translate into a relevant loss of its resistance capacity against this fatigue delamination phenomenon, in its initiation phase. On the other hand, the crack growth rates of the material subjected to different periods of exposure to a saline environment are similar and higher than those obtained for the material without exposure.

Dysregulation of synaptic and developmental transcriptomic/proteomic profiles upon depletion of MUNC18-1.

Absence of presynaptic protein MUNC18-1 (gene: Stxbp1) leads to neuronal cell death at an immature stage before synapse formation. Here, we performed transcriptomic and proteomic profiling of immature Stxbp1 knockout (KO) cells to discover which cellular processes depend on MUNC18-1. Hippocampi of Stxbp1 KO mice showed cell-type specific dysregulation of 2123 transcripts primarily related to synaptic transmission and immune response. To further investigate direct, neuron-specific effects of MUNC18-1 depletion, a proteomic screen was performed on murine neuronal cultures at two developmental timepoints prior to onset of neuron degeneration. 399 proteins were differentially expressed, which were primarily involved in synaptic function (especially synaptic vesicle exocytosis) and neuron development. We further show that many of the downregulated proteins upon loss of MUNC18-1 are normally upregulated during this developmental stage. Thus, absence of MUNC18-1 extensively dysregulates the transcriptome and proteome, primarily affecting synaptic and developmental profiles. Lack of synaptic activity is unlikely to underlie these effects, as the changes were observed in immature neurons without functional synapses, and minimal overlap was found to activity-dependent proteins. We hypothesize that presence of MUNC18-1 is essential to advance neuron development, serving as a 'checkpoint' for neurons to initiate cell death in its absence.Significance StatementPresynaptic protein MUNC18-1 is essential for neuronal functioning. Pathogenic variants in its gene, STXBP1, are among the most common found in patients with developmental delay and epilepsy. To discern the pathogenesis in these patients, a thorough understanding of MUNC18-1's function in neurons is required. Here, we show that loss of MUNC18-1 results in extensive dysregulation of synaptic and developmental proteins in immature neurons before synapse formation. Many of the downregulated proteins are normally upregulated during this developmental stage. This indicates that MUNC18-1 is a critical regulator of neuronal development, which could play an important role in the pathogenesis of STXBP1 variant carriers.

[Faecal occult blood test in symptomatic patients in primary care: A retrospective study in a healthcare area of Toledo]. / Sangre oculta en heces en pacientes sintomáticos en Atención Primaria: Un estudio retrospectivo en el área sanitaria de Toledo.

AIM: To review referral protocol in symptomatic patients from primary care of using 15µgHb/g faeces threshold with three consecutive samples in faecal occult blood (FOB) test. To compare test utility using current recommendations of 10µgHb/g faeces threshold and one sample. MATERIAL AND METHODS: A retrospective observational study was designed, including FOB samples of symptomatic patients from primary care. Samples were analyzed at the biochemistry laboratory in 2017. Seven hundred and fifteen patients tested positive and 925 patients negative. Exclusion criteria were secondary care request and patients under the age of 18. Descriptive analysis was performed of FOB results and clinical data about request and colonoscopy. FOB test's diagnostic utility was studied for different threshold (10 and 15µgHb/g faeces) in the same population. RESULTS: FOB positivity rate was 22.8% and cancer detection rate was 11%. However, the number of samples does not modify diagnostic precision. Negative predictive value is higher with 10µgHb/g faeces threshold. CONCLUSIONS: Correct patient selection and optimal threshold increase cancer detection rate. The protocol with 10µgHb/g faeces threshold and one sample collection for symptomatic patients from primary care improves the FOB test's purpose.

Unique and Additive Effects of Family and School Victimization on Child-to-Parent Violence.

In the study of child-to-parent violence (CPV), the perspective of the victimized aggressor has not been analyzed in depth, and the impact of different contexts of victimization even less so. The aim of this study was to examine the unique and additive effects of family victimization (direct and vicarious) and school victimization (bullying and cyberbullying) on predicting CPV toward fathers and mothers. The sample included 3,142 adolescents aged 12-18 years (M age = 14.32) from schools in southern Spain. The participants completed the Child-to-Parent Violence Questionnaire adolescent version, the Violence Exposure Scale, and the European Bullying/Cyberbullying Intervention Project Questionnaires. The findings showed that independently, both family and school victimization predicted CPV, with direct family victimization being the best predictor, and that jointly, contributed to a significant improvement in prediction, explaining approximately 20% of CPV. Furthermore, a correspondence was found between the type of violence experienced and the type of violence perpetrated. It is necessary to study the profile of the victimized aggressor in CPV in order to design interventions adapted to the specific needs of this profile.

Profile of the Victimized Aggressors in Child-to-Parent Violence: Differences According to the Type of Victimization.

Background/Objective: One of the main predictors of child-to-parent violence (CPV) is childhood victimization. Recent research indicates the need to study different types of CPV aggressors. However, the distinctive characteristics of the profile of the victimized aggressor and whether these characteristics differ according to the type of victimization have not been yet analyzed. Were examined differences between four types of CPV aggressors: with family victimization, with school victimization, with polyvictimization, and without victimization experiences. Method: A total of 1,559 Spanish adolescents aged between 12 and 18 years participated. Results: Compared to nonvictimized aggressors, victimized aggressors generally exercise more reactive and instrumental CPV and show more insecure parental attachment and less emotional and coping competencies. Additionally, among the types of victimization, polyvictimized aggressors show worse adjustment compared to those with a unique type of victimization. There are also significant differences according to the gender of the aggressor; however, the interaction effect between the type of aggressor and gender is not significant. Conclusions: Considering the profile of the victimized aggressor and the type of victimization experienced in CPV can provide valuable empirical information for the approach of differential explanatory mechanisms and for the design of prevention and intervention strategies adapted to the needs of this profile.

Antecedentes/Objetivo: Uno de los principales predictores de la violencia filio-parental (VFP) es la victimización infantil. Investigaciones recientes señalan la necesidad de estudiar diferentes tipos de agresores en la VFP. Sin embargo, todavía no se han analizado las características distintivas del perfil del agresor victimizado y si estas características también difieren según el tipo de victimización. Se examinaron diferencias entre cuatro tipos de agresores de VFP: con victimización familiar, con victimización escolar, con polivictimización y sin experiencias de victimización. Método: Participaron 1.559 adolescentes españoles con edades comprendidas entre 12 y 18 años. Resultados: El agresor victimizado, respecto al no victimizado, ejerce más VFP reactiva e instrumental, muestra un apego parental más inseguro y menos habilidades emocionales y de afrontamiento. Por tipos de victimización, los agresores polivictimizados muestran peor ajuste respecto a aquellos con un único tipo de victimización. Se encuentran diferencias significativas según el género de los agresores, sin embargo, el efecto de interacción entre el tipo de agresor y el género no fue significativo. Conclusiones: Considerar en la VFP el perfil del agresor victimizado, así como el tipo de victimización experimentada, puede proporcionar información empírica valiosa tanto para el planteamiento de mecanismos explicativos diferenciales como para el diseño de estrategias de prevención e intervención adaptadas a las necesidades de este perfil.

Differential Profile of Specialist Aggressor versus Generalist Aggressor in Child-to-Parent Violence.

Research on violence in general highlights the need to differentiate between those aggressors who only show specialized violence in the family context and those who also show generalized violence in other contexts outside the family. However, in the phenomenon of child-to-parent violence (CPV), the distinctive characteristics of this profile have not been yet analyzed. The aim of this study was to identify the typology of specialist aggressor versus the typology of generalist aggressor and examine whether they differ in their characteristics. A total of 1559 CPV aggressors participated, with ages between 12 and 18 years, of whom 22.4% exerted violence only towards parents (specialist aggressors) and 77.6% also exerted violence towards peers (generalist aggressors). The results show that specialized violence and generalized violence seem to follow different patterns according to age. The generalists were characterized by a more negative profile than the specialists. Specifically, the former showed more CPV and for more reasons, both reactive and proactive. Regarding individual characteristics, they obtained lower levels of emotional intelligence and resilience. Concerning family characteristics, they presented higher levels of insecure parental attachment and parental violence (direct and observed). The predictive variables retained in the regression model represented approximately 16.4% of the variation in the type of aggressor. This study supports the classification based on the specificity versus generality of violence, as it was found that specialist and generalist CPV aggressors differ significantly in their characteristics. It is considered that the findings could help to identify the differential mechanisms through which both types of aggressors have developed CPV. Further analysis of this profile can be of great use for the design of intervention and prevention programs adapted to the needs of each typology.