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1.

Current challenges in the discovery of treatments against Mayaro fever.

Marques, Rafael Elias; Shimizu, Jacqueline Farinha; Nogueira, Maurício Lacerda; Vasilakis, Nikos.

Expert Opin Ther Targets; : 1-12, 2024 May 08.

Artículo en Inglés | MEDLINE | ID: mdl-38714500

2.

Phenotypical Screening of an MMV Open Box Library and Identification of Compounds with Antiviral Activity against St. Louis Encephalitis Virus.

Sotorilli, Giuliana Eboli; Gravina, Humberto Doriguetto; de Carvalho, Ana Carolina; Shimizu, Jacqueline Farinha; Fontoura, Marina Alves; Melo-Hanchuk, Talita Diniz; Cordeiro, Artur Torres; Marques, Rafael Elias.

Viruses; 15(12)2023 12 13.

Artículo en Inglés | MEDLINE | ID: mdl-38140657

3.

Structural and molecular biology of Sabiá virus.

Bezerra, Eduardo Hs; Melo-Hanchuk, Talita D; Marques, Rafael Elias.

Exp Biol Med (Maywood); 248(19): 1624-1634, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37937408

4.

Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients.

Cambier, Seppe; Beretta, Fabio; Pörtner, Noëmie; Metzemaekers, Mieke; de Carvalho, Ana Carolina; Martens, Erik; Kaes, Janne; Aelbrecht, Celine; Jacobs, Cato; Van Mol, Pierre; Wauters, Els; Meersseman, Philippe; Hermans, Greet; Marques, Rafael Elias; Vanaudenaerde, Bart; Vos, Robin; Wauters, Joost; Gouwy, Mieke; Proost, Paul.

Cell Mol Life Sci; 80(8): 234, 2023 Jul 28.

Artículo en Inglés | MEDLINE | ID: mdl-37505242

5.

Antiviral Activity of Quercetin Hydrate against Zika Virus.

Saivish, Marielena Vogel; Menezes, Gabriela de Lima; da Silva, Roosevelt Alves; Fontoura, Marina Alves; Shimizu, Jacqueline Farinha; da Silva, Gislaine Celestino Dutra; Teixeira, Igor da Silva; Mistrão, Natalia Franco Bueno; Hernandes, Victor Miranda; Rahal, Paula; Sacchetto, Lívia; Pacca, Carolina Colombelli; Marques, Rafael Elias; Nogueira, Maurício Lacerda.

Int J Mol Sci; 24(8)2023 Apr 19.

Artículo en Inglés | MEDLINE | ID: mdl-37108665

6.

Competing interests during the key N-glycosylation of 6-chloro-7-deaza-7-iodopurine for the synthesis of 7-deaza-2'-methyladenosine using Vorbrüggen conditions.

Naciuk, Fabrício Fredo; Nascimento, Andrey Fabricio Ziem; Rocha, Rebeca Paiva Froes; Rustiguel, Joane Kathelen; Coimbra, Lais Durço; Marques, Rafael Elias; Bruder, Marjorie.

Front Chem; 11: 1163486, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37035111

7.

Different biological effects of exposure to far-UVC (222 nm) and near-UVC (254 nm) irradiation.

Tavares, Renata Spagolla Napoleão; Adamoski, Douglas; Girasole, Alessandra; Lima, Ellen Nogueira; da Silva Justo-Junior, Amauri; Domingues, Romênia; Silveira, Ana Clara Caznok; Marques, Rafael Elias; de Carvalho, Murilo; Ambrosio, Andre Luis Berteli; Leme, Adriana Franco Paes; Dias, Sandra Martha Gomes.

J Photochem Photobiol B; 243: 112713, 2023 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-37086566

8.

The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito.

Cereghino, Chelsea; Roesch, Ferdinand; Carrau, Lucía; Hardy, Alexandra; Ribeiro-Filho, Helder V; Henrion-Lacritick, Annabelle; Koh, Cassandra; Marano, Jeffrey M; Bates, Tyler A; Rai, Pallavi; Chuong, Christina; Akter, Shamima; Vallet, Thomas; Blanc, Hervé; Elliott, Truitt J; Brown, Anne M; Michalak, Pawel; LeRoith, Tanya; Bloom, Jesse D; Marques, Rafael Elias; Saleh, Maria-Carla; Vignuzzi, Marco; Weger-Lucarelli, James.

PLoS Pathog; 19(4): e1010491, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-37018377

9.

Characterization of Systemic Disease Development and Paw Inflammation in a Susceptible Mouse Model of Mayaro Virus Infection and Validation Using X-ray Synchrotron Microtomography.

de Carvalho, Ana Carolina; Dias, Carlos Sato B; Coimbra, Laís D; Rocha, Rebeca P F; Borin, Alexandre; Fontoura, Marina A; Carvalho, Murilo; Proost, Paul; Nogueira, Maurício L; Consonni, Sílvio R; Sesti-Costa, Renata; Marques, Rafael Elias.

Int J Mol Sci; 24(5)2023 Mar 02.

Artículo en Inglés | MEDLINE | ID: mdl-36902230

10.

Caffeic Acid Has Antiviral Activity against Ilhéus Virus In Vitro.

Saivish, Marielena Vogel; Pacca, Carolina Colombelli; da Costa, Vivaldo Gomes; de Lima Menezes, Gabriela; da Silva, Roosevelt Alves; Nebo, Liliane; da Silva, Gislaine Celestino Dutra; de Aguiar Milhim, Bruno Henrique Gonçalves; da Silva Teixeira, Igor; Henrique, Tiago; Mistrão, Natalia Franco Bueno; Hernandes, Victor Miranda; Zini, Nathalia; de Carvalho, Ana Carolina; Fontoura, Marina Alves; Rahal, Paula; Sacchetto, Lívia; Marques, Rafael Elias; Nogueira, Maurício Lacerda.

Viruses; 15(2)2023 02 10.

Artículo en Inglés | MEDLINE | ID: mdl-36851709

11.

Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor.

Mercaldi, Gustavo Fernando; Bezerra, Eduardo Henrique Salviano; Batista, Fernanda Aparecida Heleno; Tonoli, Celisa Caldana Costa; Soprano, Adriana Santos; Shimizu, Jacqueline Farinha; Nagai, Alice; da Silva, Jaqueline Cristina; Filho, Helder Veras Ribeiro; do Nascimento Faria, Jéssica; da Cunha, Marcos Guilherme; Zeri, Ana Carolina Mattos; Nascimento, Andrey Fabricio Ziem; Proenca-Modena, José Luiz; Bajgelman, Marcio Chaim; Rocco, Silvana Aparecida; Lopes-de-Oliveira, Paulo Sérgio; Cordeiro, Artur Torres; Bruder, Marjorie; Marques, Rafael Elias; Sforça, Mauricio Luis; Franchini, Kleber Gomes; Benedetti, Celso Eduardo; Figueira, Ana Carolina Migliorini; Trivella, Daniela Barretto Barbosa.

Sci Rep; 12(1): 18500, 2022 11 02.

Artículo en Inglés | MEDLINE | ID: mdl-36323732

12.

SARS-CoV-2 infected children form early immune memory responses dominated by nucleocapsid-specific CD8+ T cells and antibodies.

Lima, Karina; Fontoura, Julia C; de Souza, Priscila Oliveira; Fazolo, Tiago; Hilario, Gabriel; Zorzetto, Renata; Rodrigues Junior, Luiz C; Coimbra, Lais D; Borin, Alexandre; Bispo-Dos-Santos, Karina; Granja, Fabiana; Marques, Rafael Elias; Zavaglia, Gabriela Oliveira; Fernandes, Ingrid Rodrigues; Varela, Fernanda Hammes; Polese-Bonatto, Marcia; Tonini, Maiko Luís; Ikeda do Carmo, Greice Madeleine; de Almeida, Walquiria Aparecida Ferreira; Borges, Thiago J; Nakaya, Helder I; Proenca-Modena, José Luiz; Callegari-Jacques, Sidia Maria; Scotta, Marcelo Comerlato; Stein, Renato T; Bonorino, Cristina.

Front Immunol; 13: 1033364, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36405692

13.

SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner.

Saccon, Tatiana Dandolini; Mousovich-Neto, Felippe; Ludwig, Raissa Guimarães; Carregari, Victor Corasolla; Dos Anjos Souza, Ana Beatriz; Dos Passos, Amanda Stephane Cruz; Martini, Matheus Cavalheiro; Barbosa, Priscilla Paschoal; de Souza, Gabriela Fabiano; Muraro, Stéfanie Primon; Forato, Julia; Amorim, Mariene Ribeiro; Marques, Rafael Elias; Veras, Flavio Protasio; Barreto, Ester; Gonçalves, Tiago Tomazini; Paiva, Isadora Marques; Fazolini, Narayana P B; Onodera, Carolina Mie Kawagosi; Martins Junior, Ronaldo Bragança; de Araújo, Paulo Henrique Cavalcanti; Batah, Sabrina Setembre; Viana, Rosa Maria Mendes; de Melo, Danilo Machado; Fabro, Alexandre Todorovic; Arruda, Eurico; Queiroz Cunha, Fernando; Cunha, Thiago Mattar; Pretti, Marco Antônio M; Smith, Bradley Joseph; Marques-Souza, Henrique; Knittel, Thiago L; Ruiz, Gabriel Palermo; Profeta, Gerson S; Fontes-Cal, Tereza Cristina Minto; Boroni, Mariana; Vinolo, Marco Aurélio Ramirez; Farias, Alessandro S; Moraes-Vieira, Pedro Manoel M; Bizzacchi, Joyce Maria Annichino; Teesalu, Tambet; Chaim, Felipe David Mendonça; Cazzo, Everton; Chaim, Elinton Adami; Proença-Módena, José Luiz; Martins-de-Souza, Daniel; Osako, Mariana Kiomy; Leiria, Luiz Osório; Mori, Marcelo A.

Nat Commun; 13(1): 5722, 2022 09 29.

Artículo en Inglés | MEDLINE | ID: mdl-36175400

14.

UV 254 nm is more efficient than UV 222 nm in inactivating SARS-CoV-2 present in human saliva.

Sesti-Costa, Renata; Negrão, Cyro von Zuben; Shimizu, Jacqueline Farinha; Nagai, Alice; Tavares, Renata Spagolla Napoleão; Adamoski, Douglas; Costa, Wanderley; Fontoura, Marina Alves; da Silva, Thiago Jasso; de Barros, Adriano; Girasole, Alessandra; de Carvalho, Murilo; Teixeira, Veronica de Carvalho; Ambrosio, Andre Luis Berteli; Granja, Fabiana; Proença-Módena, José Luiz; Marques, Rafael Elias; Dias, Sandra Martha Gomes.

Photodiagnosis Photodyn Ther; 39: 103015, 2022 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-35843562

15.

Predicting Antigenic Peptides from Rocio Virus NS1 Protein for Immunodiagnostic Testing Using Immunoinformatics and Molecular Dynamics Simulation.

Saivish, Marielena Vogel; Menezes, Gabriela de Lima; Costa, Vivaldo Gomes da; Silva, Gislaine Celestino Dutra da; Marques, Rafael Elias; Nogueira, Maurício Lacerda; Silva, Roosevelt Alves Da.

Int J Mol Sci; 23(14)2022 Jul 12.

Artículo en Inglés | MEDLINE | ID: mdl-35887029

16.

Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds.

Borin, Alexandre; Coimbra, Laís D; Bispo-Dos-Santos, Karina; Naciuk, Fabrício F; Fontoura, Marina; Simeoni, Camila L; Gomes, Giovanni V; Amorim, Mariene R; Gravina, Humberto D; Shimizu, Jacqueline Farinha; Passos, Amanda S C; de Oliveira, Isadora M; de Carvalho, Ana Carolina; Cardoso, Alisson Campos; Parise, Pierina L; Toledo-Teixeira, Daniel A; Sotorilli, Giuliana E; Persinoti, Gabriela F; Claro, Ingra Morales; Sabino, Ester C; Alborghetti, Marcos R; Rocco, Silvana A; Franchini, Kleber G; de Souza, William M; Oliveira, Paulo S L; Cunha, Thiago M; Granja, Fabiana; Proença-Módena, José Luiz; Trivella, Daniela B B; Bruder, Marjorie; Cordeiro, Artur T; Marques, Rafael Elias.

Virulence; 13(1): 1031-1048, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-35734825

17.

Structural dynamics of SARS-CoV-2 nucleocapsid protein induced by RNA binding.

Ribeiro-Filho, Helder Veras; Jara, Gabriel Ernesto; Batista, Fernanda Aparecida Heleno; Schleder, Gabriel Ravanhani; Costa Tonoli, Celisa Caldana; Soprano, Adriana Santos; Guimarães, Samuel Leite; Borges, Antonio Carlos; Cassago, Alexandre; Bajgelman, Marcio Chaim; Marques, Rafael Elias; Trivella, Daniela Barretto Barbosa; Franchini, Kleber Gomes; Figueira, Ana Carolina Migliorini; Benedetti, Celso Eduardo; Lopes-de-Oliveira, Paulo Sergio.

PLoS Comput Biol; 18(5): e1010121, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35551296

18.

Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza.

Cambier, Seppe; Metzemaekers, Mieke; de Carvalho, Ana Carolina; Nooyens, Amber; Jacobs, Cato; Vanderbeke, Lore; Malengier-Devlies, Bert; Gouwy, Mieke; Heylen, Elisabeth; Meersseman, Philippe; Hermans, Greet; Wauters, Els; Wilmer, Alexander; Schols, Dominique; Matthys, Patrick; Opdenakker, Ghislain; Marques, Rafael Elias; Wauters, Joost; Vandooren, Jennifer; Proost, Paul.

JCI Insight; 7(1)2022 01 11.

Artículo en Inglés | MEDLINE | ID: mdl-34793331

19.

Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses.

Fazolo, Tiago; Lima, Karina; Fontoura, Julia C; de Souza, Priscila Oliveira; Hilario, Gabriel; Zorzetto, Renata; Júnior, Luiz Rodrigues; Pscheidt, Veridiane Maria; de Castilhos Ferreira Neto, Jayme; Haubert, Alisson F; Gambin, Izza; Oliveira, Aline C; Mello, Raissa S; de Bastos Balbe E Gutierres, Matheus; Gassen, Rodrigo Benedetti; Coimbra, Lais Durço; Borin, Alexandre; Marques, Rafael Elias; Sartor, Ivaine Tais Sauthier; Zavaglia, Gabriela Oliveira; Fernandes, Ingrid Rodrigues; Nakaya, Helder I; Varela, Fernanda Hammes; Polese-Bonatto, Márcia; Borges, Thiago J; Callegari-Jacques, Sidia Maria; da Costa, Marcela Santos Correa; de Araujo Schwartz, Jaqueline; Scotta, Marcelo Comerlato; Stein, Renato T; Bonorino, Cristina.

Nat Commun; 12(1): 6844, 2021 11 25.

Artículo en Inglés | MEDLINE | ID: mdl-34824230

20.

Neutrophil Recruitment and Participation in Severe Diseases Caused by Flavivirus Infection.

Fontoura, Marina Alves; Rocha, Rebeca Fróes; Marques, Rafael Elias.

Life (Basel); 11(7)2021 Jul 20.

Artículo en Inglés | MEDLINE | ID: mdl-34357089

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