RESUMEN
The importance of exfoliative cytology in the diagnosis of cancer of the oesophagus is stressed. The examination uses a straightforward, economical technique and, in association with traditional investigations, offers diagnostic positivity of close to 100%. The interest in exfoliative oesophageal cytology does not derive solely from its confirmation of clinically certain oesophageal cancer, but from the fact that it offers early diagnosis outside of dysphagic symptomatology. Its field of use is thus extended and it proves to be a complementary but indubitably useful technique for diseases of the oesophago-gastric tract, particularly in those presenting high cancerization risk. Its use is therefore recommended for the screening of oesophageal cancer.
Asunto(s)
Citodiagnóstico , Neoplasias Esofágicas/diagnóstico , Citodiagnóstico/instrumentación , Citodiagnóstico/métodos , Diagnóstico Diferencial , Enfermedades del Esófago/diagnóstico , Hernia Hiatal/diagnóstico , Humanos , Trastornos del Movimiento/diagnóstico , Úlcera Péptica/diagnósticoRESUMEN
PIP: 30-40 mg tamoxifen were administered orally in 86 postmenopausal women with late breast malignancy who were found to be resistant to standard endocrine and chemotherapy 2 months previous to this treatment. Vaginal smears were taken before and after 30-45 days treatment. A zero pyknotic index was seen before treatment. After tamoxifen, the index regularly increased to values between 10-30% reaching 50% in 4 cases and 80% in 1. Smears became atrophic within 2 months of withdrawal of treatment. 32% of the patients responded, showing an objective tumor regression. It is unclear whether the tumor is reacting to tamoxifen as if it were an estrogen.^ieng