RESUMEN
The mastocytosis is a disease characterized by an increase in mast cell number, and may present in childhood. It is classified as cutaneous or systemic mastocytosis. Cutaneous mastocytosis generally is selected in childhood. It is important to be aware of systemic complications. Systemic mastocytosis is adult-onset and its clinical presentations is caused by histamine, leucotrienes, prostaglandins and other mediators' release. The treatment is directed at symptomatic relief. Several cases are reported at Hospital Infantil de México Federico Gómez. Only 3 cases are presented of these benign child-onset diseases.
Asunto(s)
Mastocitosis , Edad de Inicio , Niño , Femenino , Antagonistas de los Receptores Histamínicos/uso terapéutico , Liberación de Histamina , Humanos , Lactante , Masculino , Mastocitosis/clasificación , Mastocitosis/diagnóstico , Mastocitosis/tratamiento farmacológico , Mastocitosis/epidemiología , Mastocitosis/patologíaRESUMEN
We choose 68 children with diagnosis of atopic dermatitis according to Hanifin's criteria, then they were sent to ophthalmologic exploration and were investigated other clinical data that could be related with ocular disturbances. The positive result for cataracts was found in three patients (4.4%) all of them females, 11, 12 and 18 years old respectively, with around 9 years of the onset of the disease. They were considered as severe according to the same criteria, all of them had familiar history of atopic diseases and tendency to generalize and to present eczematous phase in any moment of the evolution. These findings are similar to those reported by other authors and we remark the importance of recognizing risk factors in patients with this dermatosis to send opportunely to a periodic ophthalmologic evaluation.