Detalles de la búsqueda
1.
Quinolinyl-based multitarget-directed ligands with soluble epoxide hydrolase and fatty acid amide hydrolase inhibitory activities: Synthetic studies and pharmacological evaluations.
Heliyon;
10(11): e32262, 2024 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38912512
2.
Effects of sEH inhibition on the eicosanoid and cytokine storms in SARS-CoV-2-infected mice.
FASEB J;
38(10): e23692, 2024 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-38786655
3.
The Role of Autophagy in Human Uveal Melanoma and the Development of Potential Disease Biomarkers and Novel Therapeutic Paradigms.
Biomedicines;
12(2)2024 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38398064
4.
Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality.
J Med Chem;
67(3): 2095-2117, 2024 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38236416
5.
Biosynthesis of magnetosome-nanobody complex in Magnetospirillum gryphiswaldense MSR-1 and a magnetosome-nanobody-based enzyme-linked immunosorbent assay for the detection of tetrabromobisphenol A in water.
Anal Bioanal Chem;
416(1): 141-149, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37934249
6.
Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy.
J Enzyme Inhib Med Chem;
38(1): 2274797, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37975322
7.
Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA.
J Pharm Anal;
13(9): 1013-1023, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37842656
8.
The Generation of a Nanobody-Based ELISA for Human Microsomal Epoxide Hydrolase.
Int J Mol Sci;
24(19)2023 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37834144
9.
Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress.
Biomed Pharmacother;
168: 115667, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37826940
10.
Adamantyl-ureas with pyrazoles substituted by fluoroalkanes as soluble epoxide hydrolase inhibitors.
J Fluor Chem;
2662023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37638129
11.
Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol Ratios as Indices of Soluble Epoxide Hydrolase Activity.
Int J Mol Sci;
24(13)2023 Jun 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37445935
12.
Development of a sandwich ELISA for the specific quantitation of hemagglutinin (HA)-tagged proteins during their inducible expression in Escherichia coli.
Anal Bioanal Chem;
415(23): 5563-5574, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37505234
13.
Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury.
J Hazard Mater;
458: 131890, 2023 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37406527
14.
Regulatory lipid vicinal diols counteract the biological activity of epoxy fatty acids and can act as biomarkers and mechanisms for disease progression.
Pharmacol Ther;
248: 108454, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37268114
15.
Aflatoxin B1 Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity.
Int J Mol Sci;
24(12)2023 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37373086
16.
Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice.
Biochem Biophys Res Commun;
667: 64-72, 2023 07 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37209564
17.
Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits.
J Chem Inf Model;
63(10): 3209-3225, 2023 05 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37141492
18.
PROTAC-Mediated Selective Degradation of Cytosolic Soluble Epoxide Hydrolase Enhances ER Stress Reduction.
ACS Chem Biol;
18(4): 884-896, 2023 04 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36947831
19.
Development of a Genetically Encoded Magnetic Platform in Magnetospirillum gryphiswaldense MSR-1 for Downstream Processing of Protein Expression System.
Res Sq;
2023 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36993437
20.
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
ACS Cent Sci;
9(3): 440-456, 2023 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36968547