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1.
Br J Surg ; 99(2): 263-9, 2012 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-22052254

RESUMEN

BACKGROUND: Ileal pouch-anal anastomosis (IPAA) is considered the surgical treatment of choice for patients with ulcerative colitis. Quality of life (QoL) and health status are the most important patient-related outcomes. Studies investigating QoL are often cross-sectional and focus on health status. This longitudinal study evaluated QoL and health status after IPAA for ulcerative colitis and compared these with reference data from a healthy population. METHODS: Patients with ulcerative colitis who underwent a pouch operation between 2003 and 2008 completed validated questionnaires for QoL and health status. Questionnaires were completed before pouch surgery, and 6, 12, 24 and 36 months after operation. The effect of IPAA on QoL and health status was analysed, and data were compared with reference values from the healthy Dutch population. RESULTS: Data were obtained for 30 of the 32 patients. Six months after IPAA, QoL was at least comparable with that of the reference population in four of six domains. Twelve months after IPAA, overall QoL had improved, supported by findings in three QoL domains. Six months after IPAA, health status was comparable to that of the reference population in three of eight dimensions, and after 3 years it was at least comparable in five dimensions. CONCLUSION: QoL and health status increased after IPAA and reached levels comparable with those of the healthy reference population in a majority of domains and dimensions. QoL was restored first after IPAA, followed by health status.


Asunto(s)
Colitis Ulcerosa/cirugía , Reservorios Cólicos , Estado de Salud , Calidad de Vida , Adulto , Anastomosis Quirúrgica , Femenino , Humanos , Masculino , Persona de Mediana Edad , Países Bajos , Proctocolectomía Restauradora/métodos , Adulto Joven
2.
Hernia ; 15(1): 19-22, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21061139

RESUMEN

BACKGROUND: Chronic pain is the main drawback of the Lichtenstein procedure for inguinal hernia repair, with a reported incidence of 15-40%. The transinguinal pre-peritoneal (TIPP) technique seems to be associated with less chronic pain, comparable to the total extra peritoneal (TEP) technique. The aim of this study was to evaluate 3 years of TIPP and Lichtenstein experience since the start of our Hernia Center Brabant in January 2006. METHODS: Patient records of unilateral primary inguinal anterior hernia corrections (TIPP and Lichtenstein) performed since the opening of Hernia Center Brabant (2006-2008) were evaluated in a retrospective study. ASA class 4 and 5, <18 years, recurrences and bilateral hernias were excluded. In the TIPP technique, a Polysoft™ Hernia Patch was placed into the preperitoneal space using an anterior protocol led approach. The Lichtenstein technique was performed as described by Amid [Amid et al (1996) Eur J Surg 162:447-453] and modified with a soft mesh. One of the hernia surgeons decided peroperatively which technique to perform. Baseline characteristics and postoperative complications were assessed retrospectively. The attempted follow up period was 6 months. Chronic pain was assessed in both groups as mild (VAS 1-3), moderate (VAS 4-6) or severe (VAS 7-10). Chronic pain was defined in both groups as any pain sensation lasting longer than 3 months postoperatively, or when local injection of analgesia was necessary. Patients who did not come back because of chronic pain after regular follow up were regarded as free of pain. RESULTS: A total of 496 patients were included in this study; 225 TIPP and 271 Lichtenstein anterior inguinal hernia operations were analyzed. Data from one TIPP-patient were lost. Both groups were comparable with regard to baseline characteristics regarding age (p = 0.059), gender (p = 0.478) and ASA-classification (p = 0.104). TIPP: mean age 52.7 years, ASA-classification I: 54%, II: 36% and III: 5.3%. A total of 7.6% complications were assessed; recurrence (n = 1), bleeding (and re-operation) (n = 4); 10 patients (4.4%) experienced chronic pain. Persisting sensation loss occurred in 0.9%. Lichtenstein: mean age 57.3 years, ASA-classification I: 51%, II: 38% and III: 11%. A total of 8.5% complications were assessed; recurrence (n = 3), bleeding (and re-operation) (n = 3); 11 Lichtenstein patients (4.1%) experienced chronic pain. Persisting sensation loss occurred in 2.2%. Limitations of this retrospective study were incomplete follow up (31.3% had only one post operative visit 14 days after surgery) and these patients were further regarded as free of pain. Therefore, possible under-reporting of chronic pain could be present. The study was not double blind. CONCLUSION: This retrospective study design revealed no significantly better results for the TIPP procedure as compared to the Lichtenstein technique. The incidence of chronic pain reported in this retrospective study has been low in both groups since the opening of the Hernia Center Brabant. These results form the basis for a prospective randomized clinical trial comparing the TIPP and Lichtenstein techniques.


Asunto(s)
Hernia Inguinal/cirugía , Dolor Postoperatorio/etiología , Dolor/etiología , Enfermedad Crónica , Femenino , Humanos , Hipoestesia/etiología , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Hemorragia Posoperatoria/etiología , Recurrencia , Estudios Retrospectivos , Mallas Quirúrgicas , Procedimientos Quirúrgicos Operativos/efectos adversos , Procedimientos Quirúrgicos Operativos/métodos
3.
Dig Surg ; 26(1): 1-6, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19145081

RESUMEN

OBJECTIVE: Boerhaave's syndrome is a spontaneous rupture of the oesophagus with a lack of diagnostic and treatment consistency in the literature. Therefore, we reviewed all published literature in order to design a treatment algorithm based on the literature. STUDY DESIGN: A systematic literature review written in the English language since 1975. RESULTS: We reviewed all known literature. Treatment of the Boerhaave syndrome was divided into three categories: conservative, endoscopic and surgical approach. The survival rate of all treatments was 75, 100 and 81%, respectively. CONCLUSION: Boerhaave's syndrome should be treated endoscopically when diagnosed within 48 h and when there are no signs of sepsis. However, when a patient is diagnosed within 48 h and has a septic profile, thoracotomy with hemifundoplication and pleural/mediastinal drainage should be performed; and in case of intra-abdominal leakage, a laparotomy for local repair should be performed. When a patient is diagnosed after 48 h, conservative treatment should be followed and only when a patient gets a septic profile is surgical treatment indicated.


Asunto(s)
Enfermedades del Esófago/terapia , Algoritmos , Desbridamiento , Enfermedades del Esófago/diagnóstico , Enfermedades del Esófago/cirugía , Esofagoscopía , Esófago/cirugía , Humanos , Rotura Espontánea , Toracotomía
4.
Colorectal Dis ; 7(4): 354-9, 2005 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15932558

RESUMEN

BACKGROUND: Ileo neo rectal anastomosis (INRA) is a promising alternative for patients with familial adenomatous polyposis (FAP) to restorative proctocolectomy with its morbidity and unpredictable functional outcome to colectomy with ileo rectal anastomosis (IRA) with the continuing risk of rectal cancer. The aims of the present study were to evaluate the function of the neorectum, to assess the morbidity and complications of the operation and to determine the incidence of neorectal polyps. METHODS: Data of all patients having INRA, including bowel function and complications, were prospectively recorded. The reservoir capacity was determined repeatedly by physiologic tests. The anal sphincter complex was assessed by manometry and ultrasound examination. Evaluation of the neorectal mucosa was performed by endoscopy. RESULTS: Six patients underwent the INRA procedure for FAP. Median defaecation frequency two years postoperatively was 5.5/24 h (range 4-7) including 1/night (range 0-2). Endoscopic examination showed normal mucosa and no evidence of polyp formation in all patients. CONCLUSION: INRA affords a good functional reservoir and is accompanied by few reservoir-related complications. At a minimum follow up period of two years, no growth of polyps in the neorectum occurred.


Asunto(s)
Adenoma/epidemiología , Poliposis Adenomatosa del Colon/cirugía , Complicaciones Posoperatorias , Neoplasias del Recto/epidemiología , Adenoma/diagnóstico , Adenoma/etiología , Adenoma/prevención & control , Adolescente , Adulto , Anastomosis Quirúrgica/efectos adversos , Anastomosis Quirúrgica/métodos , Colectomía , Colonoscopía , Estudios de Factibilidad , Femenino , Humanos , Incidencia , Mucosa Intestinal/cirugía , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Recuperación de la Función , Neoplasias del Recto/diagnóstico , Neoplasias del Recto/etiología , Neoplasias del Recto/prevención & control , Resultado del Tratamiento
5.
Ned Tijdschr Geneeskd ; 149(5): 247-50, 2005 Jan 29.
Artículo en Holandés | MEDLINE | ID: mdl-15719836

RESUMEN

OBJECTIVE: To assess the necessity to operate on non-incarcerated inguinal hernia in children within 7 days of diagnosis. DESIGN: Retrospective. METHOD: Data on 360 children, 0-10 years old (104 girls and 256 boys) who were operated on for inguinal hernia between 1 January 1993-31 December 2001 at the St. Elisabeth Hospital in Tilburg, the Netherlands, were collected from the medical records. These data included sex, age, interval between diagnosis and repair, recurrence, incarceration, length of hospitalisation and complications. RESULTS: In the group of 113 children 0-1 years old, 137 inguinal hernias were repaired, ofwhich 16 were incarcerated on presentation. The interval between diagnosis and repair was known in 93 of 121 cases: 37 hernias were repaired within 7 days and 56 at a later stage. In the latter group, there was one case of secondary incarceration (1.8%; 95% CI: 0-5.4). The number needed to treat was 56. In the group of 247 children 1-10 years old, 269 inguinal hernias were repaired, of which 8 were primarily incarcerated. The interval between diagnosis and repair was known in 208 of 261 cases: 34 hernias were repaired within 7 days and 174 at a later stage. In the latter group, 3 hernias incarcerated secondarily (1.7%; 95% CI: 0-3.7). The number needed to treat was 58. In the group of non-incarcerated hernias 1 complication occurred, in the group of incarcerated hernias none. The mean length of hospitalisation of children with non-incarcerated hernia was 0.85 days, and of children with incarcerated hernia 2.4 days. CONCLUSION: In children with a non-incarcerated inguinal hernia who are waiting for an operation, the risk of secondary incarceration and complications is 2% which we do not think is enough reason to carry out an elective hernia-repair procedure within 7 days.


Asunto(s)
Hernia Inguinal/complicaciones , Hernia Inguinal/cirugía , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Complicaciones Posoperatorias/epidemiología , Factores de Tiempo , Resultado del Tratamiento
6.
Dig Surg ; 21(5-6): 371-8; discussion 379, 2004.
Artículo en Inglés | MEDLINE | ID: mdl-15499222

RESUMEN

BACKGROUND: Ileo-neorectal anastomosis (INRA), an alternative restorative procedure, was developed to reduce the pouch-related complication rate with an (at least) equal functional result. METHODS: For this surgical outcome, data of all INRA patients, including bowel function and complications, were prospectively recorded. The reservoir capacity was determined repeatedly by physiologic tests. The anal sphincter complex was assessed by manometry and ultrasound examination. Evaluation of the neorectal mucosa was performed by endoscopy. RESULTS: An INRA procedure was carried out in 39/53 selected patients (47 ulcerative colitis and 6 familial adenomatous polyposis). Fourteen UC cases were converted to ileal pouch anal anastomosis or proctectomy only, because of impossibility to completely remove the rectal mucosa or short of length of the rectal stump. The median operation time for INRA was 323 min (range 240-518), with 1,400 ml blood loss (400-4,500). The reservoirs were permanently defunctioned in 2 patients--one because of reclassification into Crohn's disease, and one with pouchitis refractory to medical treatment. In 18 out of 37 cases, web-like stenoses occurred at the mucosa-anal level, which were treated by single (9) or repeated (5) dilatation or surgical stenoplasty (2). No pouch-related complications like pelvic sepsis, fistula or sexual dysfunction occurred. Thirteen patients had episodes of 'pouchitis', successfully treated with antibiotics, and 7 other cases, with functioning reservoirs, also had proximal 'non-specific' (i.e. no histological criteria of Crohn's disease found) small bowel inflammation. The median bowel frequency decreased from 15x/24 h initially to 7x/24 h at 2 years. Continence was perfect in 24/37 cases. Twelve out of 37 cases had occasional nocturnal soiling and passive nocturnal fecal incontinence was reported by 2/37 patients. The neorectal compliance volume recovered from 12.5 ml kPa after subtotal colectomy and 11 ml/kPa at 6 months after INRA to a neorectal compliance of 24 ml/kPa at 2 years' follow-up (p < 0.002; Wilcoxon signed rank test). CONCLUSION: The INRA procedure shows a low complication rate and reasonable functional results, there was however a considerable conversion rate in these first 53 cases and a high incidence of reclassification to CD.


Asunto(s)
Colitis Ulcerosa/cirugía , Proctocolectomía Restauradora/métodos , Competencia Clínica , Femenino , Estudios de Seguimiento , Humanos , Masculino , Manometría , Resultado del Tratamiento
7.
Dig Surg ; 21(1): 60-4; discussion 65, 2004.
Artículo en Inglés | MEDLINE | ID: mdl-14707395

RESUMEN

BACKGROUND: Obstructive jaundice caused by stones is a common disorder, mostly managed by endoscopic sphincterotomy followed by cholecystectomy. The aim of this study was to evaluate whether or not clearance of the common bile duct alone is sufficient as treatment for patients with choledocholithiasis. METHODS: A cohort with 447 patients with symptomatic cholecystocholedocholithiasis, undergoing endoscopic retrograde cholangiography (ERC) and if necessary sphincterotomy (ES). In 164 patients common bile duct stones were proven and treated endoscopically, without performing a subsequent cholecystectomy. All 164 patients were free of symptoms after the endoscopic intervention. This group of patients was compared with 78 patients who underwent cholecystectomy after endoscopic treatment of common bile duct stones. Patients were followed for 1-13 years after ERC and sphincterotomy results and complications were registered. RESULTS: The ages of the 164 patients in the in situ group were significantly higher than in the cholecystectomy group and the ASA classification (American Society of Anesthesiologists) was significantly higher in the in situ patients. Mean follow-up was 70.9 months. Of the in situ patients 27 (16%) returned with biliary symptoms; 12 with common bile duct stones, three with cholangitis, and one with stenosis of Vater's papilla. Eight patients returned with cholecystitis and 3 with symptomatic cholecystolithiasis. Thirteen patients underwent cholecystectomy and 11 were managed (also) endoscopically. Minor complications were 2 wound infections and 1 bleeding after cholecystectomy. Two patients (1%) died of abdominal sepsis due to cholecystitis. Of the patients who underwent cholecystectomy, 6 (7.6%) returned during follow-up. Three patients had common bile duct stones, 2 had cholangitis and 1 patient presented with papillostenosis. Three patients needed surgical common bile duct exploration and the other 3 were treated endoscopically. After reintervention, cardiopulmonary complications were observed in 1 patient. There was no related death. CONCLUSION: When common bile duct stones are treated successfully by endoscopic sphincterotomy and patients are free of symptoms, there is no need for routine prophylactic cholecystectomy.


Asunto(s)
Colangiopancreatografia Retrógrada Endoscópica , Colecistectomía , Coledocolitiasis/cirugía , Cálculos Biliares/cirugía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Colecistectomía Laparoscópica , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos
8.
Int Urogynecol J Pelvic Floor Dysfunct ; 14(4): 244-9; discussion 249, 2003 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-14530835

RESUMEN

The aim of this study was to determine the prevalence of, and the changes in, anorectal symptoms following different modes of vaginal delivery in primiparous women. Six hundred and seventeen questionnaires were distributed to primiparous women 3-4 years after delivery. The questionnaires were designed to obtain information regarding the development of anorectal symptoms, including the type of symptoms experienced, their severity and their impact on lifestyle. A total of 479 questionnaires were returned, representing a response rate of 77.6%. Women included in the study were divided into three groups on the basis of the mode of delivery (normal vaginal, vacuum extraction and forceps). Any episode of fecal incontinence was considered to be abnormal. Following delivery, de novo incontinence developed in 22%. There was no significant difference between the three modes of vaginal delivery in terms of the development of fecal incontinence (normal vaginal delivery 22%, vacuum extraction 20%, forceps delivery 26%). Furthermore, analysis of obstetric variables could not identify one significant independent risk factor for anorectal incontinence. The results of this study suggest that instrumental vaginal deliveries are as safe as a normal vaginal delivery in terms of the development of anorectal symptoms.


Asunto(s)
Parto Obstétrico/efectos adversos , Incontinencia Fecal/epidemiología , Incontinencia Fecal/etiología , Forceps Obstétrico/efectos adversos , Adulto , Distribución por Edad , Anciano , Estudios de Cohortes , Parto Obstétrico/métodos , Incontinencia Fecal/fisiopatología , Femenino , Estudios de Seguimiento , Edad Gestacional , Humanos , Incidencia , Edad Materna , Persona de Mediana Edad , Embarazo , Probabilidad , Medición de Riesgo , Índice de Severidad de la Enfermedad , Encuestas y Cuestionarios , Extracción Obstétrica por Aspiración/efectos adversos
9.
Surg Endosc ; 16(7): 1068-72, 2002 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-11984690

RESUMEN

BACKGROUND: Common bile duct stones are still a frequent problem. Although new diagnostic and therapeutic techniques are continually being development, they remain poorly defined. Therefore, we decided to evaluate our standard method of diagnosing and treating common bile duct stones. The aim of the study was to determine the short- and long-term results of this method. METHODS: Between 1985 and 1995, 552 consecutive patients (200 men and 352 women; median age, 69 years) underwent endoscopic retrograde cholangiography (ERC) because of suspected common bile duct stones. If stones were detected, they were treated endoscopically, if possible. The results and complications of this policy were recorded. Patients were followed 1-13 years after undergoing ERC and endoscopic sphincterotomy (ES). Long-term results and complications during this period were also recorded. RESULTS: ERC was attempted in 552 patients and succeeded in 510 patients (92%): ES was attempted in 315 patients and failed in five (98%). Duct clearance was done in 271 patients; in 26 of these patients, symptoms disappeared spontaneously. Ten patients underwent common bile duct exploration. Complications occurred in 46 patients (8.3%). Mortality was 0.4%, hemorrhage occurred in 3.6%, pancreatitis in 1.4%, sepsis and cholangitis also in 1.4%, and the lithotripter basket became impacted in four patients (0.8%), necessitating to common bile duct exploration. During follow-up, 45 patients (8%) returned, 35 with recurrent stones, five with cholangitis, two with stenosis of the papilla of Vater, and one with biliary pancreatitis. In 35 cases, complications were treated endoscopically, common bile duct exploration was performed in five cases, and symptoms disappeared spontaneously in five cases. CONCLUSIONS: ERC is a safe and reliable way of diagnosing common bile duct stones, and ES is a very efficient way of treating them. Morbidity and mortality are low, and the long-term results are very good.


Asunto(s)
Colangiopancreatografia Retrógrada Endoscópica/métodos , Cálculos Biliares/cirugía , Esfinterotomía Endoscópica/métodos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Ampolla Hepatopancreática/patología , Ampolla Hepatopancreática/cirugía , Niño , Colangiopancreatografia Retrógrada Endoscópica/efectos adversos , Colangitis/etiología , Colangitis/cirugía , Enfermedades del Conducto Colédoco/cirugía , Constricción Patológica/etiología , Constricción Patológica/cirugía , Femenino , Estudios de Seguimiento , Cálculos Biliares/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Pancreatitis/etiología , Pancreatitis/cirugía , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/cirugía , Hemorragia Posoperatoria/etiología , Hemorragia Posoperatoria/cirugía , Esfinterotomía Endoscópica/efectos adversos , Insuficiencia del Tratamiento , Resultado del Tratamiento
10.
Br J Surg ; 88(6): 884-6, 2001 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-11412263

RESUMEN

BACKGROUND: Conventional repair of recurrent inguinal hernia is associated with a re-recurrence rate as high as 35 per cent. Endoscopic mesh repair has promising results regarding both recurrence and complication rates. METHODS: In a retrospective review, the results of endoscopic totally extraperitoneal repair were evaluated in 104 patients with 108 recurrent hernias. Follow-up was at least 1 year. Type of recurrence, time of occurrence after previous repair, duration of surgery, complications, duration of hospital stay and number of re-recurrences were evaluated. RESULTS: Follow-up ranged from 12 to 29 (mean 16) months. Forty-three recurrences were direct, 41 indirect and 15 combined; one was a femoral hernia. Median time to previous operation was 36 months (range 8 days to 42 years). Median duration of surgery was 63 (range 25--160) min. While there were no complications during operation, 12 patients (12 per cent) had a postoperative complication. Two direct re-recurrences (2 per cent) occurred as a result of inadequate positioning of the prosthetic mesh. CONCLUSION: The endoscopic totally extraperitoneal technique is safe and effective for the repair of recurrent inguinal hernia.


Asunto(s)
Endoscopía Gastrointestinal/métodos , Hernia Inguinal/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Tiempo de Internación , Masculino , Persona de Mediana Edad , Recurrencia , Reoperación , Estudios Retrospectivos , Mallas Quirúrgicas
11.
Eur J Surg ; 163(3): 187-90, 1997 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-9085060

RESUMEN

OBJECTIVE: To find out the incidence of complications among patients who present with femoral hernias and whether they are preventable. DESIGN: Retrospective study. SETTING: Teaching hospital, The Netherlands. SUBJECTS: 111 patients whose femoral hernias were operated on between 1 January 1983 and 31 June 1994. INTERVENTIONS: Emergency (n = 33) and elective repair (n = 78). MAIN OUTCOME MEASURES: Morbidity and mortality, and associated factors. RESULTS: Patients who underwent emergency repair were significantly older (median age 77 years, range 28-106 compared with 54, range 19-85, p < 0.001), were more likely to have cardiopulmonary disease (14/33 compared with 6/78, p < 0.001), and were more likely to need a bowel resection (9/33 compared with 0/78, p < 0.001). Three patients died in the emergency group compared with none in the elective group. CONCLUSION: An initial conservative policy led to higher subsequent morbidity and mortality because of the relatively high incidence of strangulation in older patients and those with cardiopulmonary disease. We therefore recommend elective repair as the treatment of choice.


Asunto(s)
Hernia Femoral/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Algoritmos , Procedimientos Quirúrgicos Electivos , Urgencias Médicas , Femenino , Hernia Femoral/complicaciones , Hernia Femoral/mortalidad , Hernia Femoral/terapia , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/mortalidad , Estudios Retrospectivos
12.
Ned Tijdschr Geneeskd ; 140(47): 2342-9, 1996 Nov 23.
Artículo en Holandés | MEDLINE | ID: mdl-8984398

RESUMEN

OBJECTIVE: Evaluation of the long-term results of protocol treatment of adult patients with ankle fractures. SETTING: St Elisabeth Hospital, Tilburg, the Netherlands. DESIGN: Retrospective long-term follow-up study. METHOD: All patients (n = 579) with an ankle fracture (580 fractures) in the period 1985-1989, who had not died soon after the injury and in whom the morbidity was not caused mainly by other conditions (n = 30) were treated according to a protocol which specified the indications for conservative or surgical therapy depending on the particular fracture type. After a median follow-up period of 5 years (range: 2.25-8.17 years) the treatment results could be evaluated in 92% of the patients. RESULTS: Clinically "good' or "excellent' results ranging from 79-90.5% types A, B and C fractures (according to the Swiss Arbeitsgemeinschaft für Osteosynthesefragen) were achieved. CONCLUSIONS: A broad indication for conservative, even functional (tape bandaging) treatment and restricted use of implants during osteosynthesis appear justified considering the results obtained.


Asunto(s)
Traumatismos del Tobillo/terapia , Fijación de Fractura/métodos , Fracturas Óseas/terapia , Adulto , Traumatismos del Tobillo/clasificación , Traumatismos del Tobillo/diagnóstico por imagen , Traumatismos del Tobillo/cirugía , Protocolos Clínicos , Femenino , Fracturas Óseas/clasificación , Fracturas Óseas/cirugía , Humanos , Estudios Longitudinales , Masculino , Radiografía , Estudios Retrospectivos , Resultado del Tratamiento
13.
Lancet ; 348(9025): 433-5, 1996 Aug 17.
Artículo en Inglés | MEDLINE | ID: mdl-8709782

RESUMEN

BACKGROUND: In familial adenomatous polyposis the only curative treatment is colectomy, and the choice of operation lies between restorative proctocolectomy (RPC) and colectomy with ileorectal anastomosis (IRA). The RPC procedure carries a higher morbidity but, unlike IRA, removes the risk of subsequent rectal cancer. Since the course of familial adenomatous polyposis is influenced by the site of mutation in the polyposis gene, DNA analysis might be helpful in treatment decisions. METHODS: We evaluated the incidence of rectal cancer in polyposis patients who had undergone IRA, and examined whether the requirement for subsequent rectal excision because of cancer or uncontrollable polyps was related to the site of mutation. FINDINGS: Between 1956 and mid-1995, 225 patients registered at the Netherlands Polyposis Registry had undergone IRA. In 87 of them, a pathogenetic mutation was detected. 72 patients had a mutation located before codon 1250 and 15 patients after this codon. The cumulative risk of rectal cancer 20 years after surgery was 12%, and at that time 42% had undergone rectal excision. The risk of secondary surgery was higher in patients with mutations in the region after codon 1250 than in patients with mutations before this codon (relative risk 2.7, p < 0.05). INTERPRETATION: On this evidence, IRA should be the primary treatment for polyposis in patients with mutations before codon 1250, and RPC in those with mutations after this codon.


Asunto(s)
Poliposis Adenomatosa del Colon/genética , Poliposis Adenomatosa del Colon/cirugía , Íleon/cirugía , Mutación , Neoplasias del Recto/etiología , Recto/cirugía , Adolescente , Adulto , Anciano , Anastomosis Quirúrgica , Niño , Codón , Estudios de Seguimiento , Humanos , Persona de Mediana Edad , Países Bajos , Proctocolectomía Restauradora , Sistema de Registros , Reoperación , Factores de Riesgo
14.
Injury ; 24(1): 46-8, 1993.
Artículo en Inglés | MEDLINE | ID: mdl-8432575

RESUMEN

Eleven patients with an isolated and displaced tibial fracture were treated by external fixation with a simple device to provide mobile traction. Anatomical results were good and all fractures healed uneventfully with minimal morbidity.


Asunto(s)
Fijadores Externos , Fracturas de la Tibia/cirugía , Adolescente , Adulto , Niño , Femenino , Humanos , Masculino , Radiografía , Fracturas de la Tibia/diagnóstico por imagen , Cicatrización de Heridas
15.
Ned Tijdschr Geneeskd ; 136(40): 1975-8, 1992 Oct 03.
Artículo en Holandés | MEDLINE | ID: mdl-1407182

RESUMEN

Severely comminuted intra-articular femoral fractures are usually associated with major soft-tissue damage as a part of serious multiple injuries. Surgical treatment should aim at exact anatomical restoration of the articular surface. Internal fixation should be stable so that functional after-treatment is possible, a condition of achieving an optimal result. In a period of over 7 years, 24 patients with 26 intra-articular comminuted fractures were operated on. Twenty patients had multiple injuries (ISS > 18), 11 fractures were complicated. Postoperatively, impaired wound healing occurred in three elderly patients; in two of these amputation was necessary. Considering the severity of the injury, the long-term results were good: ten of the 16 patients examined with 18 fractures recovered completely, in the other cases the functional result wa adequate to good. Surgical treatment of comminuted intra-articular fractures of the distal femur is to be adapted to the individual case; depending on the fracture type and the associated damage a selection is to be made from various implants and techniques. With consistent, individually adapted application of the current AO techniques good results can be obtained.


Asunto(s)
Placas Óseas , Fracturas del Fémur/cirugía , Fracturas Abiertas/cirugía , Adulto , Femenino , Fracturas del Fémur/diagnóstico por imagen , Curación de Fractura , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Radiografía
16.
Int J Sports Med ; 12(6): 577-80, 1991 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-1797701

RESUMEN

Eight healthy volunteers were fitted with a supportive knee brace (Push Brace 'Heavy') to one knee for a duration of four weeks wherein they were tested before, during and after the application to establish the effect of bracing on performance. The tests consisted of isokinetic strength measurement of knee flexion and extension, 60 meter dash, vertical jump height and a progressive horizontal treadmill test until exhaustion (Vmax) with determination of oxygen uptake, heart rate and plasma lactate concentration. Wearing the brace for one day, the performance indicators showed a decline compared with the test before application (base values). Sprint time was 4% longer (p less than 0.01) and Vmax 6% slower (p less than 0.01). Peak torque of knee flexion at 60 and 240 deg.sec-1 was 6% (p less than 0.05) respectively 9% (p less than 0.05) less. Peak extension torque at 60 deg.sec-1 was 9% less (p less than 0.05). While wearing the brace for four weeks, the test performances were practically identical to their base values. After removal of the brace, all test parameters were statistically similar to the base values. Heart rate at submaximal exercise levels was even lower (p less than 0.05). In conclusion, performance in sports with test-like exercise patterns is not affected by the brace tested. Bracing does not "weaken the knee" as it is widely believed in sports practice.


Asunto(s)
Tirantes , Inestabilidad de la Articulación/fisiopatología , Articulación de la Rodilla/fisiología , Adulto , Prueba de Esfuerzo , Femenino , Frecuencia Cardíaca , Humanos , Inestabilidad de la Articulación/rehabilitación , Traumatismos de la Rodilla/prevención & control , Pierna/fisiología , Masculino , Músculos/fisiología , Consumo de Oxígeno , Deportes
17.
Ned Tijdschr Geneeskd ; 134(32): 1541-4, 1990 Aug 11.
Artículo en Holandés | MEDLINE | ID: mdl-1975430

RESUMEN

In 523 consecutive patients with inversion injuries of ankle and foot, X-ray examination revealed 52 fractures. The majority of these fractures could be treated symptomatically. On the basis of clinical examination as the diagnostic tool for these ankle injuries, the need for radiological assessment was decided. All important fractures were recognized. The patient's ability to bear weight on the injured ankle, the presence of lateral malleolar tenderness and advanced age were important clinical variables. Careful physical examination can lead to a selective radiological assessment of acute ankle injuries. Superfluous X-ray procedures can be eliminated which will greatly reduce costs without detriment to patient care.


Asunto(s)
Traumatismos del Tobillo , Traumatismos de los Pies , Esguinces y Distensiones/diagnóstico por imagen , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Articulación del Tobillo/diagnóstico por imagen , Niño , Femenino , Pie/diagnóstico por imagen , Fracturas Óseas/diagnóstico por imagen , Fracturas Óseas/etiología , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Esguinces y Distensiones/complicaciones , Supinación
18.
Ned Tijdschr Geneeskd ; 134(33): 1607-11, 1990 Aug 18.
Artículo en Holandés | MEDLINE | ID: mdl-2395488

RESUMEN

The results of external fixation of 66 unstable distal radial fractures were evaluated. In the majority, the radiological results were excellent or good. There was a clear correlation between an excellent or good clinical score and the subsequent radiological result. Upper limb dystrophy which caused a considerable morbidity was found in every third patient. Unstable distal radial fractures with severe initial displacement predispose to reflex dystrophy. External fixation obviously cannot prevent this severe complication, it is even possible that tension on soft tissues, capsules and ligaments caused by ligamentotaxis might induce reflex dystrophy. Therefore, the indication for using external fixation of unstable distal radial fractures has to be defined with due caution.


Asunto(s)
Dispositivos de Fijación Ortopédica , Fracturas del Radio/terapia , Adulto , Anciano , Fractura de Colles/terapia , Femenino , Estudios de Seguimiento , Humanos , Luxaciones Articulares/complicaciones , Luxaciones Articulares/terapia , Masculino , Persona de Mediana Edad , Fracturas del Radio/complicaciones
19.
Injury ; 20(1): 29-31, 1989 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-2592061

RESUMEN

In 15 patients with acute medial (N = 8) or anteromedial (N = 7) laxity of the knee, reconstruction of the torn ligaments was combined with the use of the semitendinosus tendon as a dynamic extra-articular stabilizer. The postoperative regimen consisted of early mobilization in a mobile cast with full weight bearing. An evaluation 1 to 3 years after surgery revealed good results in 14 cases, and one fair result as graded using the Marshall score (mean score 45.3, SD 2.9). Isokinetic measurements of knee flexion and extension showed no loss of strength. Equally good results have been reported in conservatively treated isolated MCL lesions. In case of a combination of a MCL lesion and an ACL lesion the results reported are usually worse. This treatment regimen seems to be a good concept in acute anteromedial laxity of the knee and cannot be considered anything but an alternative in isolated MCL lesions.


Asunto(s)
Inestabilidad de la Articulación/cirugía , Articulación de la Rodilla/cirugía , Ligamentos Articulares/lesiones , Transferencia Tendinosa/métodos , Adulto , Anciano , Estudios de Seguimiento , Humanos , Inestabilidad de la Articulación/fisiopatología , Articulación de la Rodilla/fisiopatología , Persona de Mediana Edad
20.
Neth J Surg ; 40(6): 155-7, 1988 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-3231345

RESUMEN

The preliminary results of early functional treatment of 30 patients with a grade-II supination-eversion fracture of the ankle according to Lauge-Hansen are discussed. The treatment of all patients consisted of splint immobilization for one week, followed by the application of a functional brace (Push Brace Medium) and immediate full weight bearing and functional training. All fractures healed without complications. Ankle function, radiographic findings and anamnestic complaints were monitored. The loss of ankle function diminished to 3.2 degrees +/- 4.9 degrees plantar flexion and to 1.7 degrees +/- 5.3 degrees dorsal flexion after one year follow up, none of the patients had significant complaints of pain or swelling. Radiography showed consolidation with callus formation in all cases. The grade-II supination-eversion fracture is a stable fracture which allows early functional treatment with the support of a Push Brace Medium. This results in an inexpensive, simple and comfortable therapy. A prospective randomized clinical trial is necessary to show the advantages of functional treatment over cast immobilization. Long-term follow-up will have to ascertain the theoretic risk of posttraumatic osteo-arthritis.


Asunto(s)
Traumatismos del Tobillo , Fracturas Óseas/terapia , Supinación , Adolescente , Adulto , Anciano , Tirantes , Ambulación Precoz , Femenino , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis/prevención & control , Estudios Prospectivos , Férulas (Fijadores)
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