Asunto(s)
Sífilis , Humanos , Sífilis/complicaciones , Sífilis/diagnóstico , Sífilis/tratamiento farmacológico , GenitalesRESUMEN
Mycosis fungoides (MF) is the most prevalent subtype of primary cutaneous T-cell lymphomas (CTCLs). Sézary syndrome (SS) is another entity defined by leukaemic involvement, lymphadenopathy and erythroderma. Pegylated liposomal doxorubicin (PEG-DOXO) is an anthracycline used in the management of advanced primary CTCL, particularly in induction strategies. However, there are limited data on its effectiveness and tolerability in real-life patients. We report 36 patients who received PEG-DOXO for MF or SS in our centre, describing the patients' characteristics, response rates and tolerance to the treatment. The best overall responses were observed for the skin, with lower response rates for nodal involvement and moderate responses for blood disease. The treatment was mainly well tolerated, without severe adverse events, and no cardiotoxicity was observed on cardiac function monitoring.
Asunto(s)
Linfoma Cutáneo de Células T , Micosis Fungoide , Síndrome de Sézary , Neoplasias Cutáneas , Doxorrubicina/efectos adversos , Doxorrubicina/análogos & derivados , Humanos , Linfoma Cutáneo de Células T/patología , Micosis Fungoide/tratamiento farmacológico , Micosis Fungoide/patología , Polietilenglicoles , Síndrome de Sézary/tratamiento farmacológico , Síndrome de Sézary/patología , Neoplasias Cutáneas/patologíaAsunto(s)
Acné Vulgar , Hiperostosis , Osteítis , Sinovitis , Acné Vulgar/diagnóstico , Acné Vulgar/tratamiento farmacológico , Humanos , SíndromeAsunto(s)
Lentigo , Leucemia-Linfoma de Células T del Adulto , Linfoma Cutáneo de Células T , Neoplasias Cutáneas , Humanos , Linfoma Cutáneo de Células T/inducido químicamente , Linfoma Cutáneo de Células T/diagnóstico , Linfoma Cutáneo de Células T/tratamiento farmacológico , Anticuerpos Monoclonales Humanizados/efectos adversos , Neoplasias Cutáneas/inducido químicamente , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/tratamiento farmacológico , Leucemia-Linfoma de Células T del Adulto/patologíaAsunto(s)
COVID-19/complicaciones , Psoriasis/complicaciones , Psoriasis/tratamiento farmacológico , Adulto , Anciano , Fármacos Dermatológicos/uso terapéutico , Femenino , Humanos , Inmunosupresores/uso terapéutico , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , SARS-CoV-2 , España , Centros de Atención TerciariaRESUMEN
OBJECTIVE: We present an unusual case of emphysematous cystitis with multiple septic embolisms to several organs. METHOD AND RESULTS: Case description and selection of related pictures. Review of the existing literature. CONCLUSIONS: Emphysematous cystitis is a rare condition but potentially severe. Prognosis depends on a rapid diagnosis and treatment.