Detalles de la búsqueda
1.
T and B cell epitope analysis for the immunogenicity evaluation and mitigation of antibody-based therapeutics.
MAbs;
16(1): 2324836, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38512798
2.
Multifaceted Approach for Quantification and Enzymatic Activity of Iduronate-2-Sulfatase to Support Developing Gene Therapy for Hunter Syndrome.
AAPS J;
25(4): 61, 2023 06 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37340133
3.
Development of a Highly Sensitive Hybrid LC/MS Assay for the Quantitative Measurement of CTLA-4 in Human T Cells.
Molecules;
28(8)2023 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37110545
4.
Correction to: Insights on Droplet Digital PCR-Based Cellular Kinetics and Biodistribution Assay Support for CAR-T Cell Therapy.
AAPS J;
23(3): 51, 2021 Mar 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-33791893
5.
An Automated Multicycle Immunoaffinity Enrichment Approach Developed for Sensitive Mouse IgG1 Antibody Drug Analysis in Mouse Plasma Using LC/MS/MS.
Anal Chem;
93(16): 6348-6354, 2021 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-33848130
6.
Insights on Droplet Digital PCR-Based Cellular Kinetics and Biodistribution Assay Support for CAR-T Cell Therapy.
AAPS J;
23(2): 36, 2021 03 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33655393
7.
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-derived Xenografts.
Mol Cancer Ther;
19(10): 2079-2088, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32788205
8.
Hybrid LC-MS as a powerful tool for supporting protein bioanalysis in gene and cell therapies.
Bioanalysis;
12(14): 977-979, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32686957
9.
Pharmacokinetic Characterization and Tissue Distribution of Fusion Protein Therapeutics by Orthogonal Bioanalytical Assays and Minimal PBPK Modeling.
Molecules;
25(3)2020 Jan 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31991858
10.
An LC/MS based method to quantify DNA adduct in tumor and organ tissues.
Anal Biochem;
568: 1-6, 2019 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30579655
11.
Immunocapture-LC/MS-Based Target Engagement Measurement in Tumor Plasma Membrane.
Anal Chem;
90(22): 13564-13571, 2018 11 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30371057
12.
Perspectives on potentiating immunocapture-LC-MS for the bioanalysis of biotherapeutics and biomarkers.
Bioanalysis;
10(20): 1679-1690, 2018 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30371100
13.
A Two-Step Immunocapture LC/MS/MS Assay for Plasma Stability and Payload Migration Assessment of Cysteine-Maleimide-Based Antibody Drug Conjugates.
Anal Chem;
90(10): 5989-5994, 2018 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29688004
14.
Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models.
Clin Cancer Res;
24(9): 2159-2170, 2018 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29463553
15.
Rapid quantification of a cleavable antibody-conjugated drug by liquid chromatography/tandem mass spectrometry with microwave-assisted enzymatic cleavage.
J Pharm Biomed Anal;
128: 226-235, 2016 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27281578
16.
Pharmacokinetics of ixazomib, an oral proteasome inhibitor, in solid tumour patients with moderate or severe hepatic impairment.
Br J Clin Pharmacol;
82(3): 728-38, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27121262
17.
Automated non-stepwise preparation of bioanalytical calibration standards and quality controls using an ultra-low volume digitizing liquid dispenser.
Rapid Commun Mass Spectrom;
28(11): 1215-20, 2014 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24760562
18.
A novel dynamic flush method to reduce column-related carryover.
J Chromatogr Sci;
52(8): 950-3, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23899466
19.
Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target.
Clin Cancer Res;
18(18): 5020-30, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22811580
20.
MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma.
Mol Cancer Ther;
11(9): 2045-53, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22609854