Detalles de la búsqueda
1.
(+)-fenchol and (-)-isopinocampheol derivatives targeting the entry process of filoviruses.
Eur J Med Chem;
275: 116596, 2024 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38889610
2.
The Potential of Usnic-Acid-Based Thiazolo-Thiophenes as Inhibitors of the Main Protease of SARS-CoV-2 Viruses.
Viruses;
16(2)2024 01 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-38399993
3.
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling.
Molecules;
29(3)2024 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38338326
4.
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives.
Int J Mol Sci;
25(2)2024 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38279210
5.
Design, synthesis and antiviral evaluation of novel conjugates of the 1,7,7-trimethylbicyclo[2.2.1]heptane scaffold and saturated N-heterocycles via 1,2,3-triazole linker.
Arch Pharm (Weinheim);
357(3): e2300549, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38036303
6.
Soloxolone methyl induces apoptosis and oxidative/ER stress in breast cancer cells and target cancer stem cell population.
Turk J Biol;
47(4): 247-261, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38152618
7.
A New Stereoselective Approach to the Substitution of Allyl Hydroxy Group in para-Mentha-1,2-diol in the Search for New Antiparkinsonian Agents.
Molecules;
28(21)2023 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37959723
8.
Corrigendum: The main protease 3CLpro of the SARS-CoV-2 virus: how to turn an enemy into a helper.
Front Bioeng Biotechnol;
11: 1294266, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38026885
9.
Usnic Acid Derivatives Inhibit DNA Repair Enzymes Tyrosyl-DNA Phosphodiesterases 1 and 2 and Act as Potential Anticancer Agents.
Genes (Basel);
14(10)2023 10 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37895279
10.
Soloxolone Methyl Reduces the Stimulatory Effect of Leptin on the Aggressive Phenotype of Murine Neuro2a Neuroblastoma Cells via the MAPK/ERK1/2 Pathway.
Pharmaceuticals (Basel);
16(10)2023 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37895840
11.
Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan.
J Pharm Biomed Anal;
236: 115731, 2023 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37741072
12.
Identification and Study of the Action Mechanism of Small Compound That Inhibits Replication of Respiratory Syncytial Virus.
Int J Mol Sci;
24(16)2023 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37629115
13.
The main protease 3CLpro of the SARS-CoV-2 virus: how to turn an enemy into a helper.
Front Bioeng Biotechnol;
11: 1187761, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37456729
14.
New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan.
Int J Mol Sci;
24(11)2023 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37298106
15.
Bornyl-Containing Derivatives of Benzyloxyphenylpropanoic Acid as FFAR1 Agonists: In Vitro and In Vivo Studies.
Pharmaceutics;
15(6)2023 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37376118
16.
Development of an LC-MS/MS-based method for quantification and pharmacokinetics study on SCID mice of a dehydroabietylamine-adamantylamine conjugate, a promising inhibitor of the DNA repair enzyme.
J Pharm Biomed Anal;
234: 115507, 2023 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37331915
17.
Rational Design of New Monoterpene-Containing Azoles and Their Antifungal Activity.
Antibiotics (Basel);
12(5)2023 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37237723
18.
Synthesis and Evaluation of Hypoglycemic Activity of Structural Isomers of ((Benzyloxy)phenyl)propanoic Acid Bearing an Aminobornyl Moiety.
Int J Mol Sci;
24(9)2023 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37175725
19.
Molecular Modeling of Viral Type I Fusion Proteins: Inhibitors of Influenza Virus Hemagglutinin and the Spike Protein of Coronavirus.
Viruses;
15(4)2023 03 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37112882
20.
New Inhibitors of Respiratory Syncytial Virus (RSV) Replication Based on Monoterpene-Substituted Arylcoumarins.
Molecules;
28(6)2023 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36985645