1.
Org Lett
; 25(29): 5426-5430, 2023 Jul 28.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37458365
RESUMEN
[2 + 2]-Cycloaddition is the most straightforward approach to the construction of cyclobutanes. In this paper, the intermolecular [2 + 2]-cycloaddition reaction of 3-alkylideneindolin-2-ones with alkenes was achieved. This reaction can be used in the synthesis of 3-spirocyclobutyl oxindoles, polycyclic oxindoles, and late stage modification of some drug molecules.