RESUMEN
Objective: To describe audiological symptoms, audiometric profile, and distortion product otoacoustic emission in symptomatic patients recovering from SARS-CoV-2 infection (positive RT-PCR test) and asymptomatic patients (negative RT-PCR test). Methods: An analytical cross-sectional study was conducted using data obtained from clinical charts, physical examination, audiometry, and distortion product otoacoustic emission on 40 patients [case patients (CP)] recovering from SARS-CoV-2 infection diagnosed by a positive RT-PCR test and 22 asymptomatic participants with a negative RT-PCR test [non-case (NC)]. Results: Sixty-two patients (mean age: 31.1 and 28.2 years in the CP and NC groups, respectively) were included. All participants were young without significant comorbidities, risk factors for hearing loss or otological history. Vertigo (5%), tinnitus (17.5%) and aural fullness/hearing loss (35%) were found in the CP group. A statistically significant difference was found in specific frequencies (1000, 4000, and 8000 Hz) and pure tone average (low and high conversational frequencies with increased threshold in the PC group compared with the NC group), which was not found in distortion product otoacoustic emission. Conclusion: Audiovestibular symptoms are frequent in symptomatic patients recovering from SARS-CoV-2 infection. SARS-CoV-2 infection was consistently associated with an increased audiometric hearing threshold at specific frequencies and low tone average.
RESUMEN
La sífilis es una enfermedad de transmisión sexual, causada por la espiroqueta Treponema pallidum; debido a su complejidad, se le conoce como gran simuladora. Existen cuatro fases clínicas: primaria, secundaria, latente y terciaria. Es sensible a la penicilina, y su incidencia disminuyó a partir de la era antibiótica. Sin embargo, con la aparición del virus de inmunodeficiencia humana ha aumentado su aparición. La sífilis laríngea es una entidad rara y tiene un comportamiento clínico variable; dentro de su diagnóstico diferencial deben incluirse enfermedades granulomatosas laríngeas, como tuberculosis, sarcoidosis y el carcinoma laríngeo. Presentamos el caso de un paciente de 42 años, con cuadro de disfonía compatible con sífilis laríngea.
Syphilis is a sexually transmitted disease caused by the spirochete Treponema pallidum, due to its complexity is known as great simulator, there are four clinical stages: primary, secondary, latent and tertiary. It is sensitive to penicillin and its incidence had decreased following the advent of antibiotics. However, emergence of hiv has led to a recrudescence of the number of cases of syphilis. Laryngeal syphilis is a rare disease, has a variable clinical behavior, differential diagnosis should include laryngeal granulomatous diseases such as tuberculosis, sarcoidosis and laryngeal carcinoma. We present a case of a 42 year old male patient with dysphonia compatible with laryngeal syphilis.