Detalles de la búsqueda
1.
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2.
Proc Natl Acad Sci U S A;
121(6): e2317756121, 2024 Feb 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38300868
2.
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Cancer Discov;
14(2): 240-257, 2024 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37916956
3.
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.
Cancer Discov;
13(9): 2012-2031, 2023 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37270847
4.
Caregivers' Assessment of the Sensory Processing Patterns Exhibited by Children with Autism in the Gulf Region.
J Autism Dev Disord;
2023 May 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37171762
5.
Behavioral and Neuropsychological Evaluation of Executive Functions in Children with Autism Spectrum Disorder in the Gulf Region.
Brain Sci;
10(2)2020 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-32098341
6.
A survey of Canadian breast health professionals' recommendations for high-risk benign breast disease
Can J Surg;
62(5): 358-360, 2019 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31550104
7.
Outcomes after Surgery for Early Stage Breast Cancer in Women Staged With Preoperative Breast Magnetic Resonance Imaging According to Breast Tissue Density.
J Breast Imaging;
1(2): 115-121, 2019 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38424925
8.
Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood-Brain Barrier.
Mol Cancer Ther;
17(9): 1893-1901, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29970480
9.
TP53 mutations emerge with HDM2 inhibitor SAR405838 treatment in de-differentiated liposarcoma.
Nat Commun;
7: 12609, 2016 08 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-27576846
10.
Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Cancer Res;
75(8): 1560-6, 2015 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25712343
11.
Combination of PIM and JAK2 inhibitors synergistically suppresses MPN cell proliferation and overcomes drug resistance.
Oncotarget;
5(10): 3362-74, 2014 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-24830942
12.
Reducing persistent postoperative pain and disability 1 year after breast cancer surgery: a randomized, controlled trial comparing thoracic paravertebral block to local anesthetic infiltration.
Ann Surg Oncol;
21(3): 795-801, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24165901
13.
Improving breast diagnostic services with a Rapid Access Diagnostic and Support (RADS) program.
Ann Surg Oncol;
20(10): 3335-40, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23975290
14.
Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors.
J Clin Oncol;
30(19): 2307-13, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22547604
15.
Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.
PLoS One;
6(7): e20090, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21750698
16.
MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts.
Clin Cancer Res;
17(9): 2799-806, 2011 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21389100
17.
Perioperative myocardial ischemia and isolated systolic hypertension in non-cardiac surgery.
Can J Anaesth;
58(5): 428-35, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21347737
18.
EMT is the dominant program in human colon cancer.
BMC Med Genomics;
4: 9, 2011 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-21251323
19.
A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.
BMC Med Genomics;
3: 26, 2010 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-20591134
20.
De novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model.
Cancer Res;
69(23): 8949-57, 2009 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19903844