Memory detection with concurrent behavioral, autonomic, and neuroimaging measures in a mock crime.

Concealed information test (CIT) has been utilized for long to perform single measurements. The combination of multiple measures outperforms single measures because of the diverse cognitive processes they reflect and the reduction in random errors facilitated by multiple measures. To further explore the performance of the CIT with multiple measurements, 57 participants were recruited and randomly assigned into guilty and innocent groups. Subsequently, simultaneously recorded reaction time (RT), skin conductance responses (SCRs), heart rate (HR), and neuroimaging data were collected from functional near-infrared spectroscopy (fNIRS) to detect participants' concealed information in a standard CIT. The results demonstrated that all indicators including RT (area under the curve (AUC) = 0.87), SCRs (AUC = 0.79), HR (AUC = 0.78), and fNIRS (channel 8, AUC = 0.85) could differentiate guilty and innocent groups. Importantly, the use of multiple indicators achieved higher detection efficiency (AUC = 0.96) compared to the use of any single indicator. These results illustrate the effectiveness and feasibility of integrating multiple indicators for concealed information detection in CIT.

Lateral flow assay sensitivity and signal enhancement via laser µ-machined constrains in nitrocellulose membrane.

Lateral flow assay (LFA) is a handful diagnostic technology that can identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other common respiratory viruses in one strip, which can be tested at the point-of-care without the need for equipment or skilled personnel outside the laboratory. Although its simplicity and practicality make it an appealing solution, it remains a grand challenge to substantially enhance the colorimetric LFA sensitivity. In this work, we present a straightforward approach to enhance the sensitivity of LFA by imposing the flow constraints in nitrocellulose (NC) membranes via a number of vertical femtosecond laser micromachined microchannels which is important for prolonged specific binding interactions. Porous NC membrane surfaces were structured with different widths and densities µ-channels employing a second harmonic of the Yb:KGW femtosecond laser and sample XYZ translation over a microscope objective-focused laser beam. The influence of the microchannel parameters on the vertical wicking speed was evaluated from the video recordings. The obtained results indicated that µ-channel length, width, and density in NC membranes controllably increased the immunological reaction time between the analyte and the labeled antibody by 950%. Image analysis of the colorimetric indicators confirmed that the flow rate delaying strategy enhanced the signal sensitives by 40% compared with pristine NC LFA.

Investigating premotor corticospinal excitability in fast and slow voluntary contractions of the elbow flexors.

Corticospinal excitability (CSE) increases prior to a voluntary contraction; however, the relative contributions of premotor cortical and spinal mechanisms are poorly understood. It is unknown whether the intended voluntary contractile rate affects CSE. Eighteen young, healthy participants (nine females) completed isometric elbow flexion contractions targeting 50% maximal voluntary contraction (MVC) torque, at either fast (fast as possible) or slow (25% MVC/s) contractile rates. Participants were cued to contract with warning (red) and "GO" (green) visual signals. Magnetic and electric stimulations were applied to elicit motor evoked potentials (MEPs), cervicomedullary evoked potentials (CMEPs), and M-waves, in the surface electromyogram (EMG) recorded over the biceps brachii. MEPs and CMEPs were collected at 0, 25, 50 and 75% premotor reaction time (RT - defined as the time between the "GO" cue and onset of biceps brachii EMG) and compared to a resting baseline. MEP amplitude was greater than baseline at 75% RT (p=0.009), and CMEP amplitude was significantly increased at all RT points relative to baseline (p≤0.001). However, there were no differences in MEP and CMEP amplitudes when compared between fast and slow conditions (p≥0.097). Normalized to the CMEP, there was no difference in MEP amplitude from baseline in either contractile condition (p≥0.264). These results indicate that increased premotor CSE is a spinally-mediated response. Furthermore, premotor CSE is not influenced by the intended voluntary contractile rate. CMEP amplitudes were larger for females than males within the premotor RT period (p=0.038), demonstrating that premotor spinal excitability responses may be influenced by sex.

Are all negative words alike? Behavioral differences in processing negative words associated and not associated with physical and social pain.

Studies examining whether stimulus valence affects cognitive processing and motor responses yield mixed results, possibly due to treating negative words as a homogeneous category. Words related to pain may hold distinct status because of their relevance to survival. Thus, they offer a unique opportunity to investigate semantic influences on cognitive processing. This study aims to determine if words related to physical and social pain elicit stronger aversion than general negative words by assessing the Affective Compatibility Effect in implicit and explicit tasks. In Experiment 1, 35 participants performed a lexical decision task on 60 positive words and 60 negative words, of which 20 not related to pain, 20 related to physical pain, and 20 related to social pain. Participants held down the central key of a keyboard and released it to press a key far from the screen (avoidance condition) or close to the screen (approach condition) for words. In Experiment 2, 43 participants performed a valence evaluation task on the same words. They held down the central key and released it to press a key close to the screen for positive words and a key far from the screen for negative words (congruent condition), or the opposite (incongruent condition). In Experiment 1, we found faster RTs for social pain-related words compared to other categories. We also found faster RTs in the approach condition than in the avoidance condition, regardless of whether valence or semantics were considered as independent variables. In Experiment 2, we found faster RTs in the congruent condition than in the incongruent condition when semantics was considered as independent variable. We also found an interaction valence*condition, with faster RTs for negative words in the congruent condition than in the incongruent condition when valence was considered as independent variable. Our findings suggest that, notwithstanding pain-related words do not affect aversive behaviors compared to negative, pain-unrelated words, they are processed faster when conveying social pain. This supports the hypothesis that the cognitive system differentiates and responds congruently not only based on general semantic categories, like pain, but also possibly based on nuances within it.

Listen to the beat: Behavioral and neurophysiological correlates of slow and fast heartbeat sounds.

BACKGROUND: Listening to heartbeat sounds have been found to affect cardiac activity and behavior. However, less is known about the effects of these stimuli on brain activity and cognition. Alpha oscillations (8-13 Hz) are considered markers of cortical activation. Frontal alpha Asymmetry (FαA) reflects the valence attributed to the stimulus and the tendency to approach/avoid it. AIM: This study investigates the effects of sounds mimicking heart pulsations at different rhythms on reaction times and neurophysiological activity. METHOD: EEG data were collected during a resting-state condition and two Simple Reaction Time tasks (SRT), during which artificially generated heartbeat sounds at fast (120 bpm, FastBeat condition) or slow (60 bpm, SlowBeat condition) rhythms were administered. Alpha power was compared across the three conditions. Differences in the SRT and FαA values were examined between the FastBeat and SlowBeat conditions. RESULTS: Compared to the resting-state condition, decreased alpha activity over bilateral frontocentral regions was observed in both tasks. The comparison between the FastBeat and the SlowBeat conditions revealed faster response times, a pattern of alpha suppression over right frontal regions, and lower FαA values in the former. CONCLUSIONS: The similarity of alpha reductions elicited in the comparison between the resting-state and the two task conditions suggests that these patterns were ascribable to processes common to both conditions (SRT task, auditory stimulation). In contrast, the differences between the two conditions suggest that fast heartbeat sounds are perceived as more adverse and stressful stimuli, inducing cortical activation over regions associated with negative states and avoidant tendencies.

Light Exposure on Alertness after Wake-Up in Healthy Men: Comparing Dim, Bright, Red, and Blue Light.

INTRODUCTION: Light is a key factor in moderating human alertness, both subjective and objective. However, the methodology applies in research on the effects of exposure to light of different wavelengths and intensities on objective and subjective alertness varies greatly and evidence on objective alertness in particular is still inconclusive. Thus, the present, highly standardized within-subject laboratory study on N = 44 healthy males explored how LED light of different intensities (dim vs. bright light) and wavelengths (red vs. blue) affected objective (reaction time/RT) as well as subjective (sleepiness) alertness in the morning after wake-up. METHODS: Participants spent two separate nights in the laboratory and were exposed to either one of the two light intensities or colors for 60 min after wake-up. Additionally, they indicated their sleepiness on the Karolinska Sleepiness Scale and participated in an auditory RT task before and after light intervention. It was hypothesized that both bright and blue light would lead to greater subjective and objective alertness when compared to dim and red light, respectively. RESULTS: Results indicated that average RTs were longer for participants in the bright light condition (p = 0.004, f2 = 0.07) and that RTs decreased post-light exposure irrespective of light being dim or bright (p = 0.026, f2 = 0.07). However, dim versus bright light and RT did not interact (p = 0.758, f2 = 0.07). Chronotype was a significant covariate in the interaction of dim versus bright light and subjective sleepiness (p = 0.008, f2 = 0.22). There was no difference in RTs when comparing exposure to red or blue light (p = 0.488, f2 = 0.01). Findings on subjective sleepiness and light of different wavelengths revealed that sleepiness was reduced after light exposure (p = 0.007, f2 = 0.06), although the wavelength of light did not appear to play a role in this effect (p = 0.817, f2 = 0.06). CONCLUSION: Hence, neither of the hypotheses could be confirmed. However, they indicated that evening types might benefit from exposure to bright light regarding sleepiness, but not morning types.

An improvement of the conceptual system of the sequential events model of road crashes (i-MOSES).

Background: The circulation of vehicles, motorized or not, is a risky activity that can lead to a traffic accident in which all road users can be affected. Road accidents generate high personal, labor, health and economic costs, as well as civil, administrative and even criminal responsibilities. Therefore, it is necessary to carry out a correct investigation of these road accidents. This paper reviews one of the models used for this investigation, the sequential events model for road crashes called MOSES. This model simplifies into a single sequential analysis the actions and conditions that have generated the occurrence and correlation of events that have led to a collision between two bodies, at least one of which is a vehicle, with harmful consequences for the environment, people and things. Methods: Analyzing the road accidents that occurred in the city of Badajoz between 2018 and 2022, this work proposes a new position of the sequential events in road accidents. This new position is present in more than fifty percent of the analyzed road accidents. How this new position can improve the description of traffic accidents is tested by analyzing an actual traffic accident recorded in the city of Badajoz between a motorcycle and a car. Results: The new position has been called Trust Position (TP) and is located between the Real Perception Position (RPP) and the Decision Enforcement Position (DEP) in the sequential events model for road crashes (i-MOSES). Furthermore, in this improvement of the MOSES model (i-MOSES), the reaction time (RT) is analyzed in more depth with the PIEV (Perception, Intellection, Emotion and Volition) theory, establishing that between RPP and TP are present the phases of perception and intellection, and between TP and DEP are present the phases of emotion and volition. Conclusions: This analysis shows how the proposed i-MOSES model allows for a deeper and more effective analysis of the causes that generated the traffic accident and all its circumstances. Moreover, it provides conclusions closer to the reality of how the accident actually happened and why it could have happened, ultimately leading to preventive measures to avoid future accidents.

Effects of Supplementation with a Microalgae Extract from Phaeodactylum tricornutum Containing Fucoxanthin on Cognition and Markers of Health in Older Individuals with Perceptions of Cognitive Decline.

Phaeodactylum tricornutum (PT) is a microalgae extract that contains fucoxanthin and has been shown to enhance cognitive function in younger populations. The present study assessed if PT supplementation affects cognition in healthy, young-old, physically active adults with self-perceptions of cognitive and memory decline. METHODS: Forty-three males and females (64.3 ± 6.0 years, 79.8 ± 16.0 kg, 27.0 ± 4.0 kg/m2) with perceptions of cognitive and memory decline completed the double-blind, randomized, parallel-arm, placebo-controlled intervention clinical trial. Participants were counterbalanced by sex and BMI and randomly allocated to their respective 12-week supplementation interventions, which were either the placebo (PL) or 1100 mg/day of PT containing 8.8 mg of fucoxanthin (FX). Fasting blood samples were collected, and cognitive assessments were performed during the testing session at 0, 4, and 12 weeks of intervention. The data were analyzed by multivariate and univariate general linear model (GLM) analyses with repeated measures, pairwise comparisons, and mean changes from baseline analysis with 95% confidence intervals (CIs) to assess the clinical significance of the findings. RESULTS: FX supplementation significantly affected (p < 0.05) or exhibited tendencies toward significance (p > 0.05 to p < 0.10 with effect sizes ranging from medium to large) for word recall, picture recognition reaction time, Stroop color-word test, choice reaction time, and digit vigilance test variables. Additionally, FX supplementation promoted a more consistent clinical improvement from baseline values when examining mean changes with 95% CIs, although most differences were seen over time rather than between groups. CONCLUSIONS: The results demonstrate some evidence that FX supplementation can improve working and secondary memory, vigilance, attention, accuracy, and executive function. There was also evidence that FX promoted more positive effects on insulin sensitivity and perceptions about sleep quality with no negative effects on clinical blood panels or perceived side effects. Additional research should investigate how FX may affect cognition in individuals perceiving memory and cognitive decline. Registered clinical trial #NCT05759910.

Acupuncture Effect on Reaction-Time Changes in Parkinson's Disease Patients-Case Study Series.

Background: Parkinson's Disease (PD) is a progressive neurodegenerative condition associated with deficit in reaction time which can lead to falls, resulting in limited independence, diminished quality of life, heightened rates of institutionalization and increased healthcare costs. We aimed to examine the effects of an acupuncture protocol in motor time response after an auditory stimulus. Methods: This study employed a case series design. Reaction time to exposed rhythmic and random auditory stimuli outcomes were evaluated at six different moments over a month-long acupuncture treatment protocol using the MP 36 system from Biopac Systems. Results: We observed a tendency to have more pronounced improvements in the time response in the more affected side of the body compared with the contralateral one. Patients tended to show better values of response to random auditory stimuli compared to rhythmic auditory ones. We also observed a tendency to obtain better results when considering the accumulative effects of the acupuncture protocol. Conclusions: Our findings indicated a possible role of reaction time as a sensitive and useful tool for motor function assessment in PD patients. Also, from our results, we concluded that the acupuncture protocol used may lead to an improvement in efficacy of motor response after aleatory and rhythmic stimulus; we also found a tendency for a higher efficacy of acupuncture in random stimuli responses in the first stages of the disease. However, further in-depth research, including a statistical evaluation with a larger participant pool, is necessary to validate and confirm these promising results.

The Relationships Between Reaction Time Scores and False Start Penalties of Offensive Linemen in the National Football League (NFL).

Each year in the United States, many factors are considered in the National Football League's draft process, including scouting reports, interviews, medical tests, and measures of players' strength, speed, anthropometry, and personality. Recently, an increased emphasis has been placed on players' psychometrically measured cognitive abilities. Historically, offensive linemen have been excluded from NFL research, since they do not have individual performance statistics. In this study, we attempted to fill that research gap by investigating correlates of offensive linemen's measured vigilance/impulsivity. We obtained archival player data from 85 offensive linemen in the years from 2014-2021 prior to each of these players' NFL draft. We then used false start penalties per game (FSPG) as an index of their vigilance/impulsivity (and general success) on the field, and we related those values to Reaction Time tests through hierarchical multiple regression analyses. After controlling for draft placement, these players' higher accuracy on a Choice Reaction Time task accounted for a statistically significant percentage of the variance associated with their FSPG statistics. We discuss the practical utility for player development of these and other cognitive assessments now used in the NFL.

Assessing the stability of responding of male mice in the touchscreen 5 choice serial reaction time task: Focus on premature responding.

The five-choice serial reaction time task (5CSRTT) is a test of attention that provides a well-validated ancillary measure of impulsive action, measured by premature responses. The task has been adapted for mice in touchscreen operant boxes, which is thought to offer improved test-retest reliability. Few studies have assessed the long-term stability of performance, including premature responding in this version of the task. We used the touchscreen 5CSRTT to conduct longitudinal testing of stability of premature responding following repeated behavioral and pharmacological manipulations. Male C57BL/6J mice were trained on a baseline version of the 5CSRTT. They were then tested on versions of the task in which the stimulus duration was reduced, and inter-trial intervals were elongated or varied within-session. Premature responding was subsequently tested following administration of pharmacological agents known to bi-directionally affect attention and impulsive action-cocaine, atomoxetine, and yohimbine. Mice were lastly re-tested 6 months later using the 5CSRTT with elongated inter-trial intervals. A reduced stimulus duration impacted attention, with reduced accuracy and increased omissions, but had no effect on premature responding. Both elongating and varying the inter-trial interval within-session increased premature responses. Mice showed similar and stable levels of increased premature responding 6 months later. Cocaine increased premature responding, though less than previously reported in rats. Atomoxetine reduced premature responding. Yohimbine had no effect on premature responding in the baseline task but decreased premature responding when tested using an elongated inter-trial interval. Overall, these results highlight that the touch screen adaptation of the 5CSRTT is an effective method for longitudinal testing of attention and impulsive action and remains sensitive to performance changes arising from repeated pharmacological and behavioral challenges.

Atlas-Based Structural Disconnectomes Are Associated with Cognitive Performance in Brain Tumors.

Background: Brain tumors are associated with impaired cognitive functioning, which may result from disruptions in brain structural connectivity. Estimating structural disconnections is a more advantageous representation of tumor impact and can be performed indirectly through normative brain atlases. Materials and Methods: Using a publicly available dataset of glioma and meningioma patient MRI scans and tumor masks, latent correlations were estimated between measures of structural disconnection and attention-based cognitive functioning. These measures included gray matter (GM) parcel damage, white matter tract damage, GM parcel-to-parcel disconnections, and reaction time (RTI) as part of the Cambridge Neuropsychological Test Automated Battery to assess attention. Results: Preprocessing pipelines with two different methods of minimizing the pathology impact on MRI normalization were utilized: cost-function masking and lesion filling. The results across both pipelines were nearly consistent, with significant correlations mainly found between RTI measures and the damage to the left inferior fronto-occipital and uncinate fasciculus, as well as the left prefrontal-visual disconnections. Conclusions: This alludes to the importance of left-hemispheric prefrontal-visual coupling in attention-based tasks, particularly those involving object- and feature-based attention.

Effects of muscle quantity, muscle quality, and phase angle on whole-body reaction time in 5164 adults aged 20-91 years.

PURPOSE: Muscle quantity, defined as appendicular lean mass (ALM); muscle quality, defined as the ratio of muscle strength to ALM; and bioelectrical impedance analysis (BIA)-derived phase angle (PhA) are determinants of physical performance. We examined whether muscle quality indices were significant predictors of the whole-body reaction time (WBRT) in healthy female and male adults aged 20-91 years. METHODS: Data from 5164 adults (2869 women and 2295 men; mean age ± standard deviation, 60.9 ± 15.6 years) were analyzed. Height and weight were measured, and body mass index was calculated. ALM was estimated using a previously validated 8-electrode multi-frequency BIA. PhA was measured at 50 kHz using a BIA device. Knee extension strength (KES), leg extension power (LEP), and flexibility were examined. The ALM to weight (ALM/weight), KES to ALM (KES/ALM), and LEP to KES (LEP/KES) ratios were calculated. In the WBRT test, participants were asked to stand on a force plate and jump upright as quickly as possible in response to a light stimulus. The WBRT was divided into the response initiation and motion execution phases. RESULTS: ALM/weight, KES/ALM, LEP/KES, PhA, and flexibility were significant independent predictors of WBRT and the time of the motion execution phase (p < 0.001). However, PhA was not a significant predictor of the time of response initiation phase. CONCLUSION: Muscle quantity (ALM/weight), muscle quality (KES/ALM and LEP/KES), PhA, and flexibility are determinants of WBRT test performance, particularly in the motion execution phase.

Temporal characteristics of turbulent flow and moth orientation behaviour patterns with fluent simulation and moth-based moving model simulation.

Objective: Previous research has explored the pheromone release patterns of female moths, revealing species-specific release frequencies and the transmission of temporal information through odourant plumes in turbulent flows. Varying the release frequency during the orientation process results in distinct orientation behaviours. Studies on moth movement patterns have determined that encounters and deviations from odour plumes elicit distinct reactions; the time interval between each movement pattern is measured as the "reaction time," and the interval between each detection and loss of odourant plume is measured as the "gap length." Methods: We simulated turbulent flow at various release frequencies. Our efforts focused on establishing a model that could simulate the joint orientation movement under turbulent flow and intermittent plumes. We built an agent moving mechanism, including wind velocity information, with particular reference to the temporal parameter and orientation success efficiency. Results: We calculated the time threshold of each burst in different simulations under different wind velocities and release frequencies. The time structure characteristics of the plume along the turbulent flow vary depending on the distance from the source. We simulated walking agents in a turbulent environment and recorded their behaviour processes. The reaction time, release interval, and time threshold were related to the orientation results. Conclusion: On the basis of previous experimental results and our simulations, we conclude that the designated interval time likely enhances search efficiency. The complex and dynamic natural environment presents various opportunities for using this unique odour-source searching capability in different scenarios, potentially improving the control systems of odour-searching robots.

Effects of different doses of caffeine on cognitive performance in healthy physically active individuals.

PURPOSE: Caffeine is a potent central nervous system stimulant that increases the activity of the prefrontal cortex and can improve various cognitive skills. An improvement in these cognitive skills can lead to further benefits in athletic performance. Therefore, it is necessary to clarify the dose-response of caffeine on cognitive performance. This study aimed to determine the effects of different doses of caffeine on sport-related cognitive aspects. METHODS: Twenty-nine healthy physically active young adults were recruited. All participants completed three trials under the following conditions: (a) placebo, (b) 3 mg/kg, or (c) 6 mg/kg body mass of caffeine. In each trial, different cognitive abilities were evaluated with the following battery of tests: reaction time (Dynavision™ D2), anticipation (Bassin Anticipation Timer), sustained attention (Go/No-Go and Eriksen Flanker Test) and memory tests. Moreover, the side effects and the perceived sensation index were recorded 24 h after each test. RESULTS: Reaction time only improved following 6 mg/kg of caffeine intake (Physical reaction time: -0.04 s, 95% CI -0.08 to -0.01 s, P = 0.036, d = 0.5; Motor reaction time: -0.04 s, 95% CI -0.07 to -0.01 s, P = 0.008, d = 0.6) compared to the placebo condition. Anticipation, sustained attention, and memory were not affected after either caffeine dose intake (all P > 0.05). In addition, the 6 mg/kg dose of caffeine augmented the occurrence of the side effects of increased activeness (P = 0.046) and nervousness (P = 0.001). CONCLUSION: Acute intake of 6 mg/kg caffeine is effective in improving reaction time despite increasing the occurrence of side effects in healthy physically active young adults. STUDY REGISTRATION: This study has been registered in ClinicalTrials whose ID is: NCT05995314 (2023-08-08).

Evaluating mental chronometry as a quantitative measure of information processing in early childhood autism.

OBJECTIVES: Mental chronometry is the scientific study of cognitive processing speed measured by reaction time (RT), which is the elapsed time between the onset of a stimulus and an individual's response. This study aims at measuring the RT among young children with autism spectrum disorders (ASD) and comparing it with normal (typically developing) children. METHODS: 60 ASD children were selected from different ASD centers, and 60 normal children were selected from different kindergartens for participation in this study. Participants were aged 3-6 years old. The RT was measured using the Fitlight trainer device. The findings were statistically evaluated using independent t-tests and ANOVA tests. RESULT: Significant differences (p < 0.0001) were found between both groups in all tasks, and ASD children demonstrated slower RT compared to the normal group. The RT measured through three senses (visual, auditory, and touch) for ASD and normal were 3.64 ± 2.16, 13.19 ± 2.41(trial), 1835.23 ± 757.95, 697.12 ± 87.83 (second), and 1550.89 ± 499.76, 752.67 ± 124.02 (second) respectively. CONCLUSION: The evaluated RT showed significant impairment in RT among ASD in comparison to normal children and this was true for the three senses. The Fitlight trainer could be used to assess RT and stimulus-response among ASD children in various cognitive tasks. Similar studies, involving larger samples from different areas and involving other sense organs, are indicated to confirm the results.

The Effect of Short-Term Exposure to Lower Body Positive Pressure on Motor Signal Processing, Reaction Times, and Cardiovascular Parameters in Healthy Volunteers Using Medical Anti-shock Trousers.

Microgravity, as experienced during spaceflight has notable effects on the cognition and cardiovascular systems. However, its effect on motor signal processing is not known. In this study, we planned to study the effect of microgravity simulation with a lower body positive pressure of 50 mmHg on motor signal processing, reaction times, and cardiovascular parameters. Thirty healthy human volunteers participated in this investigation, and continuous ECG and non-invasive blood pressure were measured at baseline, during, and after a lower body positive pressure of 50 mmHg. Bereitschafts potential was recorded at 0 mmHg and 50 mmHg pressure values in a lower body positive pressure (LBPP) suit. Parameters recorded during the pressure change of 0 mmHg to 50 mmHg were RR interval, heart rate, systolic blood pressure, diastolic blood pressure, stroke volume, cardiac output, and peripheral vascular resistance. Heart rate variability (HRV) was calculated from RR intervals during resting and pressure of 50 mm of Hg. We also compared simple and choice reaction times for visual and auditory stimuli during 50 mmHg LBPP exposure with baseline recording. We found a significant increase in systolic blood pressure, stroke volume, and cardiac output from baseline at 50 mmHg of LBPP. We found a significant change in amplitude and area of Bereitschaft potential at the C4 site at 50 mmHg of LBPP. We found a significant change in low-frequency power (LF) as compared to the baseline in HRV. Simple reaction time (visual & auditory) and auditory choice reaction time were improved at 50 mmHg of LBPP. Motor signal processing and reaction time were improved during 50 mmHg of lower body positive pressure exposure.

Associations between whole-body reaction time, maximum jump height, and skeletal muscle mass when reaction time and jump height are investigated as a complex.

[Purpose] This study aimed to investigate the association between whole-body reaction time and maximum jump height as elements of agility performance requiring maximum jumping when measured separately as closed-skill sports or as a complex of open-skill sports and their association with skeletal muscle mass. [Participants and Methods] This study included 54 healthy adult volunteers. Reaction time and jump height in response to a light stimulus were measured separately (the "simple condition") and simultaneously (the "complex condition"), and the associations between the values under these two conditions were investigated. The associations between the skeletal muscle mass and the two elements under both conditions were also investigated. [Results] No correlation was found between the reaction times measured under the simple and complex conditions; however, a significant correlation was evident for the jump height. Skeletal muscle mass correlated significantly with jump height but not with reaction time. [Conclusion] The study results suggest that the relationship between open- and closed-skill sports differs between reaction time and jump height. Therefore, closed-skill sports training may be insufficient for improving open-skill sports and cognitive function and may affect decision-making strategies.

Cervical Sensorimotor Function Tests Using a VR Headset-An Evaluation of Concurrent Validity.

Sensorimotor disturbances such as disturbed cervical joint position sense (JPS) and reduced reaction time and velocity in fast cervical movements have been demonstrated in people with neck pain. While these sensorimotor functions have been assessed mainly in movement science laboratories, new sensor technology enables objective assessments in the clinic. The aim was to investigate concurrent validity of a VR-based JPS test and a new cervical reaction acuity (CRA) test. Twenty participants, thirteen asymptomatic and seven with neck pain, participated in this cross-sectional study. The JPS test, including outcome measures of absolute error (AE), constant error (CE), and variable error (VE), and the CRA test, including outcome measures of reaction time and maximum velocity, were performed using a VR headset and compared to a gold standard optical motion capture system. The mean bias (assessed with the Bland-Altman method) between VR and the gold standard system ranged from 0.0° to 2.4° for the JPS test variables. For the CRA test, reaction times demonstrated a mean bias of -19.9 milliseconds (ms), and maximum velocity a mean bias of -6.5 degrees per seconds (°/s). The intraclass correlation coefficients (ICCs) between VR and gold standard were good to excellent (ICC 0.835-0.998) for the JPS test, and excellent (ICC 0.931-0.954) for reaction time and maximum velocity for the CRA test. The results show acceptable concurrent validity for the VR technology for assessment of JPS and CRA. A slightly larger bias was observed in JPS left rotation which should be considered in future research.

Individual differences in working memory capacity and temporal preparation: A secondary reanalysis.

The ability to prepare and maintain an optimal level of preparedness for action, across some unknown duration, is critical for human behavior. Temporal preparation has historically been analyzed in the context of reaction time (RT) experiments where the interval varies between the start of the trial, or foreperiod (FP), and the required response. Two main findings have come out of such paradigms: the variable FP effect (longer RTs to shorter vs. longer FPs) and the sequential FP effect (longer RTs when shorter FPs follow longer FPs). Several theoretical views of these FP effects have been proposed with some suggesting a dissociation while others argue for an implicit process driven by memory traces. One possible method to test these views of FP effects is to examine how individual differences in working memory capacity (WMC) moderate such effects. To this end, I reanalyzed data from three studies in which participants completed measures of WMC and a simple RT task with a variable FP. Results suggest that individual differences in WMC were related to the magnitude of the variable FP and the sequential FP effect in two of three individual studies. A "mega-analysis" provided supportive evidence for a relationship between WMC and both forms of FP effects. The present combined experimental-individual differences study provides a novel approach to better understand how and why individuals vary in temporal preparation ability. Through leveraging several large-scale databases unseen in FP research, I provide a new way of understanding FP effects and response timing more generally.