Detalhe da pesquisa
1.
A Fast-Binding, Functionally Reversible, COX-2 Radiotracer for CNS PET Imaging.
ACS Cent Sci;
10(5): 1105-1114, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38799654
2.
mARC1 in MASLD: Modulation of lipid accumulation in human hepatocytes and adipocytes.
Hepatol Commun;
8(5)2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38619429
3.
BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy.
Mol Metab;
66: 101633, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36356832
4.
Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state.
Nat Commun;
13(1): 3778, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773251
5.
Systematic identification of biomarker-driven drug combinations to overcome resistance.
Nat Chem Biol;
18(6): 615-624, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332332
6.
Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J Med Chem;
64(15): 11148-11168, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34342224
7.
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles.
Nat Chem Biol;
16(5): 497-506, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32231343
8.
Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS.
Mol Cell Proteomics;
18(10): 2089-2098, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409669
9.
Conservation of the structure and function of bacterial tryptophan synthases.
IUCrJ;
6(Pt 4): 649-664, 2019 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31316809
10.
Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.
Cell Rep;
22(11): 2924-2936, 2018 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29539421
11.
A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat Chem Biol;
13(9): 943-950, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671682
12.
Positive Regulation of Interleukin-1ß Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation.
Cell Rep;
20(1): 224-235, 2017 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28683316
13.
Reactive Oxygen Species-Producing Myeloid Cells Act as a Bone Marrow Niche for Sterile Inflammation-Induced Reactive Granulopoiesis.
J Immunol;
198(7): 2854-2864, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28235862
14.
G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling.
J Exp Med;
213(10): 1999-2018, 2016 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27551153
15.
Myeloid cell-derived reactive oxygen species externally regulate the proliferation of myeloid progenitors in emergency granulopoiesis.
Immunity;
42(1): 159-71, 2015 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25579427
16.
Cigarette smoke (CS) and nicotine delay neutrophil spontaneous death via suppressing production of diphosphoinositol pentakisphosphate.
Proc Natl Acad Sci U S A;
110(19): 7726-31, 2013 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23610437
17.
Rapid LC-MS drug metabolite profiling using bioreactor particles.
Methods Mol Biol;
987: 129-34, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23475673
18.
Reactive oxygen species-induced actin glutathionylation controls actin dynamics in neutrophils.
Immunity;
37(6): 1037-49, 2012 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23159440
19.
Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion.
Mol Biol Cell;
23(7): 1219-30, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323291
20.
Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format.
Anal Chem;
81(24): 9921-9, 2009 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19904994