Detalhe da pesquisa
1.
Cell envelope structural and functional contributions to antibiotic resistance in Burkholderia cenocepacia.
J Bacteriol;
206(4): e0044123, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38501654
2.
The mechanism of action of auranofin analogs in B. cenocepacia revealed by chemogenomic profiling.
Microbiol Spectr;
12(2): e0320123, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38206016
3.
Profiling cell envelope-antibiotic interactions reveals vulnerabilities to ß-lactams in a multidrug-resistant bacterium.
Nat Commun;
14(1): 4815, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558695
4.
The Burkholderia contaminans prevalent phenotypes as possible markers of poor clinical outcomes in chronic lung infection of children with cystic fibrosis.
Pathog Dis;
812023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36963774
5.
ABT-MPNN: an atom-bond transformer-based message-passing neural network for molecular property prediction.
J Cheminform;
15(1): 29, 2023 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36843022
6.
A machine learning model trained on a high-throughput antibacterial screen increases the hit rate of drug discovery.
PLoS Comput Biol;
18(10): e1010613, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36228001
7.
Deep clustering of small molecules at large-scale via variational autoencoder embedding and K-means.
BMC Bioinformatics;
23(Suppl 4): 132, 2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35428173
8.
The Phenylacetic Acid Catabolic Pathway Regulates Antibiotic and Oxidative Stress Responses in Acinetobacter.
mBio;
13(3): e0186321, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35467424
9.
Deep learning-driven prediction of drug mechanism of action from large-scale chemical-genetic interaction profiles.
J Cheminform;
14(1): 12, 2022 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35279211
10.
Gradients in gene essentiality reshape antibacterial research.
FEMS Microbiol Rev;
46(3)2022 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35104846
11.
Identification of putative essential protein domains from high-density transposon insertion sequencing.
Sci Rep;
12(1): 962, 2022 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35046497
12.
New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates.
Antibiotics (Basel);
10(12)2021 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34943654
13.
Improved Dynamic Range of a Rhamnose-Inducible Promoter for Gene Expression in Burkholderia spp.
Appl Environ Microbiol;
87(18): e0064721, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34190606
14.
Comparative genomics of ST5 and ST30 methicillin-resistant Staphylococcus aureus sequential isolates recovered from paediatric patients with cystic fibrosis.
Microb Genom;
7(3)2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33599606
15.
Phenylacetyl Coenzyme A, Not Phenylacetic Acid, Attenuates CepIR-Regulated Virulence in Burkholderia cenocepacia.
Appl Environ Microbiol;
85(24)2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31585996
16.
The Effect of 2-Thiocyanatopyridine Derivative 11026103 on Burkholderia Cenocepacia: Resistance Mechanisms and Systemic Impact.
Antibiotics (Basel);
8(4)2019 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31546596
17.
A Broad-Host-Range CRISPRi Toolkit for Silencing Gene Expression in Burkholderia.
ACS Synth Biol;
8(10): 2372-2384, 2019 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31491085
18.
Synthesis and antibiotic activity of novel acylated phloroglucinol compounds against methicillin-resistant Staphylococcus aureus.
J Antibiot (Tokyo);
72(5): 253-259, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30760838
19.
Competitive Fitness of Essential Gene Knockdowns Reveals a Broad-Spectrum Antibacterial Inhibitor of the Cell Division Protein FtsZ.
Antimicrob Agents Chemother;
62(12)2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297366
20.
A c-di-GMP-Modulating Protein Regulates Swimming Motility of Burkholderia cenocepacia in Response to Arginine and Glutamate.
Front Cell Infect Microbiol;
8: 56, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29541628