Detalhe da pesquisa
1.
Editorial: Role of glia in neurodevelopmental disorders.
Front Cell Neurosci;
18: 1404362, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38665373
2.
Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer's Disease.
J Alzheimers Dis;
96(1): 77-91, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37742639
3.
Purinergic ionotropic P2X7 and metabotropic glutamate mGlu5 receptors crosstalk influences pro-inflammatory conditions in microglia.
Eur J Pharmacol;
938: 175389, 2023 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36435235
4.
Editorial: Novel Therapeutic Potential for Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), Vasoactive Intestinal Peptide (VIP) and Related Peptides in Cognition Deficits.
Front Cell Neurosci;
15: 748970, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34588958
5.
Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome.
Eur J Neurosci;
2021 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33949019
6.
Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT7 Receptor.
Int J Mol Sci;
21(24)2020 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33348850
7.
Privileged scaffold-based design to identify a novel drug-like 5-HT7 receptor-preferring agonist to target Fragile X syndrome.
Eur J Med Chem;
199: 112395, 2020 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32442850
8.
Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Hippocampal Synaptic Transmission and Plasticity: New Therapeutic Suggestions for Fragile X Syndrome.
Front Cell Neurosci;
13: 524, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827422
9.
Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome.
Cereb Cortex;
29(8): 3241-3252, 2019 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30137253
10.
Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome.
Front Mol Neurosci;
11: 353, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333723
11.
Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice.
Nat Commun;
8(1): 1103, 2017 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29062097
12.
Purinergic P2Y1 Receptors Control Rapid Expression of Plasma Membrane Processes in Hippocampal Astrocytes.
Mol Neurobiol;
54(6): 4081-4093, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27318677
13.
A subnanomolar concentration of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine.
Neuroscience;
340: 551-562, 2017 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27816700
14.
Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome.
Front Behav Neurosci;
9: 65, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25814945
15.
5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders.
Front Cell Neurosci;
8: 250, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25221471
16.
Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism.
Neurosci Biobehav Rev;
46 Pt 2: 228-41, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24548786
17.
Synthesis, modelling and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-d-aspartate receptors.
Bioorg Med Chem;
22(3): 1040-8, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24411196
18.
Synthesis and biological characterization of 3-substituted 1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors. Part 2.
J Med Chem;
55(23): 10532-9, 2012 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23140383
19.
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.
Biol Psychiatry;
72(11): 924-33, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22817866
20.
Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors.
J Med Chem;
54(24): 8702-6, 2011 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22050212