Detalhe da pesquisa
1.
Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing.
STAR Protoc;
4(4): 102165, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37729058
2.
Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells.
bioRxiv;
2023 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292647
3.
In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities.
Blood Cancer Discov;
4(2): 150-169, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36468984
4.
Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models.
Blood Adv;
7(16): 4514-4517, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36477552
5.
JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States.
Cancer Res;
83(2): 264-284, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409824
6.
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells.
Nat Biotechnol;
40(2): 189-193, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33927418
7.
Author Correction: CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells.
Nat Biotechnol;
40(2): 273, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33986547
8.
Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.
Blood Cancer Discov;
2(1): 54-69, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33604581
9.
A Code of Ethics for Gene Drive Research.
CRISPR J;
4(1): 19-24, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571044
10.
High throughput single-cell detection of multiplex CRISPR-edited gene modifications.
Genome Biol;
21(1): 266, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33081820
11.
Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.
Sci Transl Med;
12(561)2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938797
12.
Technologies and Computational Analysis Strategies for CRISPR Applications.
Mol Cell;
79(1): 11-29, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32619467
13.
Publisher Correction: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Nat Biotechnol;
38(7): 901, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32541959
14.
Therapeutic base editing of human hematopoietic stem cells.
Nat Med;
26(4): 535-541, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32284612
15.
Assessment of computational methods for the analysis of single-cell ATAC-seq data.
Genome Biol;
20(1): 241, 2019 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31739806
16.
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.
Cell Stem Cell;
25(5): 622-638.e13, 2019 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31588046
17.
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature;
569(7757): 576-580, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31092926
18.
Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Nat Med;
25(5): 776-783, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30911135
19.
CRISPResso2 provides accurate and rapid genome editing sequence analysis.
Nat Biotechnol;
37(3): 224-226, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30809026
20.
Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Nat Biotechnol;
37(3): 276-282, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30742127