Detalhe da pesquisa
1.
Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens.
ACS Med Chem Lett;
6(8): 930-5, 2015 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26288696
2.
X-ray crystal structures of Escherichia coli RNA polymerase with switch region binding inhibitors enable rational design of squaramides with an improved fraction unbound to human plasma protein.
J Med Chem;
58(7): 3156-71, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25798859
3.
Novel rapidly diversifiable antimicrobial RNA polymerase switch region inhibitors with confirmed mode of action in Haemophilus influenzae.
J Bacteriol;
194(20): 5504-12, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22843845