Detalhe da pesquisa
1.
Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria.
J Inherit Metab Dis;
2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38487984
2.
Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria.
Sci Rep;
12(1): 16083, 2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167967
3.
Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria.
Mol Genet Metab;
2022 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35680516
4.
Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria.
Mol Genet Metab Rep;
30: 100846, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35242577
5.
Treatment of osteoporotic fractures in alkaptonuria by teriparatide stimulates bone formation and decreases fracture rate - A report of two cases.
Bone Rep;
15: 101151, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34926730
6.
Osteoarthritis-Slow but Steady Steps Forward.
Calcif Tissue Int;
109(3): 241-242, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34427704
7.
Bio-processing of macroalgae Palmaria palmata: metabolite fractionation from pressed fresh material and ensiling considerations for long-term storage.
J Appl Phycol;
33(1): 533-544, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568889
8.
Frequency, diagnosis, pathogenesis and management of osteoporosis in alkaptonuria: data analysis from the UK National Alkaptonuria Centre.
Osteoporos Int;
32(5): 927-938, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33118050
9.
Alkaptonuria - Many questions answered, further challenges beckon.
Ann Clin Biochem;
57(2): 106-120, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31529982
10.
Quantification of the flux of tyrosine pathway metabolites during nitisinone treatment of Alkaptonuria.
Sci Rep;
9(1): 10024, 2019 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296884
11.
Interference of hydroxyphenylpyruvic acid, hydroxyphenyllactic acid and tyrosine on routine serum and urine clinical chemistry assays; implications for biochemical monitoring of patients with alkaptonuria treated with nitisinone.
Clin Biochem;
71: 24-30, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31228435
12.
Correction to: Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging.
Metabolomics;
15(5): 81, 2019 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31104147
13.
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging.
Metabolomics;
15(5): 68, 2019 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31037385
14.
Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis.
Osteoarthritis Cartilage;
27(8): 1244-1251, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31022456
15.
Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone.
Data Brief;
20: 1620-1628, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30263914
16.
Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone.
Mol Genet Metab;
125(1-2): 135-143, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30049652
17.
Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre.
Mol Genet Metab;
125(1-2): 127-134, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30055994
18.
Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project.
Osteoarthritis Cartilage;
26(8): 1078-1086, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29852277
19.
Serum Amino Acid Profiling in Patients with Alkaptonuria Before and After Treatment with Nitisinone.
JIMD Rep;
41: 109-117, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754208
20.
What cell wall components are the best indicators for Miscanthus digestibility and conversion to ethanol following variable pretreatments?
Biotechnol Biofuels;
11: 67, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29563970