Detalhe da pesquisa
1.
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.
Biosci Rep;
44(6)2024 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747277
2.
Water Conservation Overrides Osmotic Diuresis During SGLT2 Inhibition in Patients With Heart Failure.
J Am Coll Cardiol;
83(15): 1386-1398, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38599715
3.
Potential Underlying Mechanisms Explaining the Cardiorenal Benefits of Sodium-Glucose Cotransporter 2 Inhibitors.
Adv Ther;
41(1): 92-112, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37943443
4.
Efficacy and safety of zibotentan and dapagliflozin in patients with chronic kidney disease: study design and baseline characteristics of the ZENITH-CKD trial.
Nephrol Dial Transplant;
39(3): 414-425, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37632201
5.
Zibotentan in combination with dapagliflozin compared with dapagliflozin in patients with chronic kidney disease (ZENITH-CKD): a multicentre, randomised, active-controlled, phase 2b, clinical trial.
Lancet;
402(10416): 2004-2017, 2023 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37931629
6.
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial.
Cardiovasc Diabetol;
22(1): 330, 2023 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38017482
7.
Evaluating clinical outcomes and prognosis in patients with cirrhosis and portal hypertension: a retrospective observational cohort study.
BMJ Open Gastroenterol;
10(1)2023 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38030407
8.
APOL1 promotes endothelial cell activation beyond the glomerulus.
iScience;
26(6): 106830, 2023 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37250770
9.
Endothelin-1, Outcomes in Patients With Heart Failure and Reduced Ejection Fraction, and Effects of Dapagliflozin: Findings From DAPA-HF.
Circulation;
147(22): 1670-1683, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37039015
10.
The sodium glucose co-transporter 2 inhibitor dapagliflozin ameliorates the fluid-retaining effect of the endothelin A receptor antagonist zibotentan.
Nephrol Dial Transplant;
38(10): 2289-2297, 2023 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37102226
11.
IGFBP-7 and Outcomes in Heart Failure With Reduced Ejection Fraction: Findings From DAPA-HF.
JACC Heart Fail;
11(3): 291-304, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36592046
12.
Liver tests and outcomes in heart failure with reduced ejection fraction: findings from DAPA-HF.
Eur J Heart Fail;
24(10): 1856-1868, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36054568
13.
Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial.
Clin Transl Sci;
15(10): 2493-2504, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35971596
14.
Bilirubin levels and kidney function decline: An analysis of clinical trial and real world data.
PLoS One;
17(6): e0269970, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35727760
15.
The Adaptive Renal Response for Volume Homeostasis During 2 Weeks of Dapagliflozin Treatment in People With Type 2 Diabetes and Preserved Renal Function on a Sodium-Controlled Diet.
Kidney Int Rep;
7(5): 1084-1092, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35570989
16.
Relationship of Dapagliflozin With Serum Sodium: Findings From the DAPA-HF Trial.
JACC Heart Fail;
10(5): 306-318, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483792
17.
Effects of dapagliflozin on volume status and systemic haemodynamics in patients with chronic kidney disease without diabetes: Results from DAPASALT and DIAMOND.
Diabetes Obes Metab;
24(8): 1578-1587, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35478433
18.
Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19.
J Mol Cell Cardiol;
167: 92-96, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35339512
19.
Loop and thiazide diuretic use and risk of chronic kidney disease progression: a multicentre observational cohort study.
BMJ Open;
12(1): e048755, 2022 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35105612
20.
Predicted Cardiac Functional Responses to Renal Actions of SGLT2i in the DAPACARD Trial Population: A Mathematical Modeling Analysis.
J Clin Pharmacol;
62(4): 541-554, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34657303