Detalhe da pesquisa
1.
Characterising the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases.
medRxiv;
2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766261
2.
Selecting the right therapeutic target for kidney disease.
Front Pharmacol;
13: 971065, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36408217
3.
Pharmacogenomic study of heart failure and candesartan response from the CHARM programme.
ESC Heart Fail;
9(5): 2997-3008, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35736394
4.
Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis.
Am J Respir Crit Care Med;
206(1): 56-69, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417304
5.
Metabolic dysfunction-related liver disease as a risk factor for cancer.
BMJ Open Gastroenterol;
9(1)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35338048
6.
Rare variant contribution to human disease in 281,104 UK Biobank exomes.
Nature;
597(7877): 527-532, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34375979
7.
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank.
Nat Genet;
53(7): 942-948, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34183854
8.
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis.
Commun Biol;
4(1): 392, 2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758299
9.
Assessing the Role of Rare Genetic Variation in Patients With Heart Failure.
JAMA Cardiol;
6(4): 379-386, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326012
10.
Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing.
Circ Genom Precis Med;
13(6): e003030, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33125268
11.
Exome-Based Rare-Variant Analyses in CKD.
J Am Soc Nephrol;
30(6): 1109-1122, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085678
12.
Diagnostic Utility of Exome Sequencing for Kidney Disease.
N Engl J Med;
380(2): 142-151, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30586318
13.
ADAMTS13 predicts renal and cardiovascular events in type 2 diabetic patients and response to therapy.
Diabetes;
62(10): 3599-609, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23733198
14.
Growth differentiation factor 15 predicts future insulin resistance and impaired glucose control in obese nondiabetic individuals: results from the XENDOS trial.
Eur J Endocrinol;
167(5): 671-8, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22918303
15.
Current drug development challenges in chronic kidney disease (CKD)--identification of individualized determinants of renal progression and premature cardiovascular disease (CVD).
Nephrol Dial Transplant;
27 Suppl 3: iii81-8, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22734108
16.
Comparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytes.
PLoS One;
7(4): e35012, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22514701
17.
DNA methylation of the PITX2 gene promoter region is a strong independent prognostic marker of biochemical recurrence in patients with prostate cancer after radical prostatectomy.
J Urol;
181(4): 1678-85, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19233404
18.
IL-10 is excluded from the functional cytokine memory of human CD4+ memory T lymphocytes.
J Immunol;
179(4): 2389-96, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17675500
19.
Third Santorini conference pharmacogenomics workshop report: "Pharmacogenomics at the crossroads: what else than good science will be needed for the field to become part of Personalized Medicine?".
Clin Chem Lab Med;
45(7): 843-50, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17617025
20.
Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis.
J Urol;
177(5): 1753-8, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17437806