Detalhe da pesquisa
1.
Author Correction: Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants.
Nat Commun;
15(1): 3273, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38627431
2.
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants.
Nat Commun;
15(1): 2742, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38548752
3.
Systematic identification of biomarker-driven drug combinations to overcome resistance.
Nat Chem Biol;
18(6): 615-624, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332332
4.
Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.
Nat Genet;
53(12): 1664-1672, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34857952
5.
Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1.
Mol Cancer Res;
19(6): 1015-1025, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619228
6.
CloneSifter: enrichment of rare clones from heterogeneous cell populations.
BMC Biol;
18(1): 177, 2020 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33234154
7.
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine.
Clin Cancer Res;
26(18): 4995-5006, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631955
8.
Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization.
Cell Syst;
10(1): 52-65.e7, 2020 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31668800
9.
Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.
Cancer Cell;
36(4): 369-384.e13, 2019 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31543463
10.
Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer.
Mol Cancer Res;
17(11): 2281-2293, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31462500
11.
DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance.
J Clin Invest;
129(11): 5005-5019, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31437130
12.
A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.
Cancer Res;
79(9): 2352-2366, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819666
13.
Mutational processes shape the landscape of TP53 mutations in human cancer.
Nat Genet;
50(10): 1381-1387, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30224644
14.
A Convergence-Based Framework for Cancer Drug Resistance.
Cancer Cell;
33(5): 801-815, 2018 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29763622
15.
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.
Nat Commun;
8(1): 1324, 2017 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29109393
16.
Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool.
PLoS One;
12(1): e0170445, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28118392
17.
Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.
Cell Rep;
17(4): 1171-1183, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27760319
18.
Characterizing genomic alterations in cancer by complementary functional associations.
Nat Biotechnol;
34(5): 539-46, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27088724
19.
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
Science;
352(6282): 189-96, 2016 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27124452
20.
A functional landscape of resistance to ALK inhibition in lung cancer.
Cancer Cell;
27(3): 397-408, 2015 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25759024