Detalhe da pesquisa
1.
RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.
J Biol Chem;
: 107459, 2024 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38857861
2.
Autism Spectrum Disorder- and/or Intellectual Disability-Associated Semaphorin-5A Exploits the Mechanism by Which Dock5 Signalosome Molecules Control Cell Shape.
Curr Issues Mol Biol;
46(4): 3092-3107, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38666924
3.
A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.
NPJ Precis Oncol;
8(1): 46, 2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396251
4.
RhoG-Binding Domain of Elmo1 Ameliorates Excessive Process Elongation Induced by Autism Spectrum Disorder-Associated Sema5A.
Pathophysiology;
30(4): 548-566, 2023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38133141
5.
A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor.
Cell Death Discov;
9(1): 467, 2023 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38135680
6.
Targeting Ras-binding domain of ELMO1 by computational nanobody design.
Commun Biol;
6(1): 284, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36932164
7.
Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor.
Biochem Biophys Res Commun;
653: 12-20, 2023 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36848820
8.
Structural Insight into TNIK Inhibition.
Int J Mol Sci;
23(21)2022 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36361804
9.
Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery.
Int J Biol Macromol;
210: 172-181, 2022 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526766
10.
Structural insights into the small GTPase specificity of the DOCK guanine nucleotide exchange factors.
Curr Opin Struct Biol;
71: 249-258, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34507037
11.
Reduced efficacy of a Src kinase inhibitor in crowded protein solution.
Nat Commun;
12(1): 4099, 2021 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34215742
12.
Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex.
Sci Adv;
7(30)2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34290093
13.
Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells.
Autophagy;
17(12): 4286-4304, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33849387
14.
Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer.
Nat Commun;
12(1): 1261, 2021 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33627640
15.
A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8.
Life Sci Alliance;
4(4)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33574036
16.
Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN.
Front Immunol;
10: 1450, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31293597
17.
Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor.
Structure;
27(5): 741-748.e3, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30853411
18.
Structural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.
ChemistryOpen;
7(9): 721-727, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30214852
19.
Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye.
Sci Signal;
11(541)2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30065028
20.
Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression.
Protein Expr Purif;
150: 92-99, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29793032