Detalhe da pesquisa
1.
Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect.
J Biol Chem;
289(38): 26533-26541, 2014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25104357
2.
Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth.
J Biol Chem;
289(31): 21413-22, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24962578
3.
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex.
Mol Cell;
53(4): 534-48, 2014 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24486017
4.
Transforming growth factor ß neutralization ameliorates pre-existing hepatic fibrosis and reduces cholangiocarcinoma in thioacetamide-treated rats.
PLoS One;
8(1): e54499, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23349909
5.
TGF-ß and αvß6 integrin act in a common pathway to suppress pancreatic cancer progression.
Cancer Res;
72(18): 4840-5, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787119
6.
Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-ß.
Cancer Res;
72(16): 4119-29, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22693253
7.
Gr-1+CD11b+ cells are responsible for tumor promoting effect of TGF-ß in breast cancer progression.
Int J Cancer;
131(11): 2584-95, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22487809
8.
Anti-transforming growth factor ß antibody treatment rescues bone loss and prevents breast cancer metastasis to bone.
PLoS One;
6(11): e27090, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22096521
9.
TGF-ß regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence.
PLoS One;
6(9): e25168, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21980391
10.
TGFß1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.
Clin Cancer Res;
17(21): 6754-65, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22028490
11.
Protection from obesity and diabetes by blockade of TGF-ß/Smad3 signaling.
Cell Metab;
14(1): 67-79, 2011 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21723505
12.
Antibody targeting of TGF-ß in cancer patients.
Curr Pharm Biotechnol;
12(12): 2176-89, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21619535
13.
Tumor localization of an anti-TGF-ß antibody and its effects on gliomas.
Int J Oncol;
38(1): 51-9, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21109925
14.
Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.
Mol Cancer;
9: 122, 2010 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20504320
15.
Inhibition of TGF-ß signaling by 1D11 antibody treatment increases bone mass and quality in vivo.
J Bone Miner Res;
25(11): 2419-26, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20499365
16.
Key roles for transforming growth factor beta in melanocyte stem cell maintenance.
Cell Stem Cell;
6(2): 130-40, 2010 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20144786
17.
Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells.
Int J Cancer;
126(7): 1666-74, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19830696
18.
Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody.
Clin Cancer Res;
15(21): 6560-9, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19861451
19.
Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines.
Clin Cancer Res;
15(21): 6551-9, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19861464
20.
Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues.
Am J Pathol;
174(6): 2137-49, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19406991