Detalhe da pesquisa
1.
Structural Insights into Partial Activation of the Prototypic G Protein-Coupled Adenosine A2A Receptor.
ACS Pharmacol Transl Sci;
7(5): 1415-1425, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38751633
2.
Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs.
J Med Chem;
2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753594
3.
Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist.
Purinergic Signal;
2024 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38795223
4.
Development of an active-site titrant for SARS-CoV-2 main protease as an indispensable tool for evaluating enzyme kinetics.
Acta Pharm Sin B;
14(5): 2349-2357, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38799620
5.
Empowering Voices: Inspiring Women in Medicinal Chemistry.
ACS Med Chem Lett;
15(4): 424-431, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38628790
6.
Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity".
ACS Pharmacol Transl Sci;
7(4): 1195-1196, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38633592
7.
Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead.
ACS Chem Biol;
19(5): 1028-1034, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38668705
8.
Empowering Voices: Inspiring Women in Medicinal Chemistry.
J Med Chem;
67(6): 4251-4258, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38456628
9.
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity.
ACS Pharmacol Transl Sci;
7(2): 493-514, 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38357286
10.
Proinflammatory chemokine CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2.
Commun Biol;
7(1): 52, 2024 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184723
11.
Diagnostic and Therapeutic Radiopharmaceuticals: A "Hot" Topic.
ACS Pharmacol Transl Sci;
7(1): 1-7, 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38230278
12.
Suberin, the hallmark constituent of bark, identified in a 45-million-year-old monkeyhair tree (Coumoxylon hartigii) from Geiseltal, Germany.
Sci Rep;
14(1): 118, 2024 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38167954
13.
Stereocontrolled access to thioisosteres of nucleoside di- and triphosphates.
Nat Chem;
16(2): 249-258, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37857844
14.
Diagnostic and Therapeutic Radiopharmaceuticals: A "Hot" Topic.
J Med Chem;
66(24): 16457-16463, 2023 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38109062
15.
Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4).
J Med Chem;
66(23): 15674-15698, 2023 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967029
16.
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability.
J Med Chem;
66(23): 16426-16440, 2023 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992202
17.
Antiplatelet Effects of Selected Xanthine-Based Adenosine A2A and A2B Receptor Antagonists Determined in Rat Blood.
Int J Mol Sci;
24(17)2023 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686188
18.
Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.
Front Immunol;
14: 1173634, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37711611
19.
Anti-Inflammatory Activities of 8-Benzylaminoxanthines Showing High Adenosine A2A and Dual A1/A2A Receptor Affinity.
Int J Mol Sci;
24(18)2023 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37762006
20.
Synthesis and biological evaluation of simplified ajudazol derivatives reveal potent 5-lipoxygenase inhibition and considerable apoptotic activity in neuroblastoma cells.
Bioorg Med Chem Lett;
94: 129464, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634760