Detalhe da pesquisa
1.
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins.
Sci Transl Med;
16(735): eadk1867, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38381847
2.
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
bioRxiv;
2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405899
3.
Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution.
Sci Signal;
16(798): eabk3516, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37582161
4.
Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
PLoS Pathog;
19(6): e1011416, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384622
5.
Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc Natl Acad Sci U S A;
120(24): e2216612120, 2023 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37276407
6.
Diversity oriented clicking delivers ß-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors.
Proc Natl Acad Sci U S A;
119(37): e2208540119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36070343
7.
Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
iScience;
25(9): 104914, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35971553
8.
Sialic Acid Ligands of CD28 Suppress Costimulation of T Cells.
ACS Cent Sci;
7(9): 1508-1515, 2021 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34584952
9.
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc Natl Acad Sci U S A;
117(31): 18431-18438, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690700
10.
An Irreversible Inhibitor to Probe the Role of Streptococcus pyogenes Cysteine Protease SpeB in Evasion of Host Complement Defenses.
ACS Chem Biol;
15(8): 2060-2069, 2020 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32662975
11.
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry.
J Am Chem Soc;
142(25): 10899-10904, 2020 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32479075
12.
Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model.
bioRxiv;
2020 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511387
13.
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.
Science;
369(6506): 956-963, 2020 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32540903
14.
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.
Proc Natl Acad Sci U S A;
116(38): 18808-18814, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484779
15.
Evidence for multiple modes of neutrophil serine protease recognition by the EAP family of Staphylococcal innate immune evasion proteins.
Protein Sci;
27(2): 509-522, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29114958
16.
The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein.
Protein Sci;
26(8): 1595-1608, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28512867
17.
(1)H, (15)N, and (13)C resonance assignments of Staphylococcus aureus extracellular adherence protein domain 4.
Biomol NMR Assign;
10(2): 301-5, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27372920
18.
Identification of peptidic inhibitors of the alternative complement pathway based on Staphylococcus aureus SCIN proteins.
Mol Immunol;
67(2 Pt B): 193-205, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26052070
19.
The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase.
J Immunol;
193(12): 6161-6171, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25381436