B-Type natriuretic peptide as a predictor of short-term mortality in on-pump coronary artery bypass grafting
Rev. bras. cir. cardiovasc
; 32(6): 462-467, Nov.-Dec. 2017. tab, graf
Article
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| ID: biblio-897954
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ABSTRACT
Abstract Objective:
The present study refers to a determination of the preoperative B-type natriuretic peptide is a predictor of short-term all-cause mortality in patients undergoing on-pump coronary artery bypass graft surgeries.Methods:
Two hundred and twenty-one patients undergoing on-pump coronary artery bypass graft surgeries were evaluated prospectively during a 30-day postoperative follow-up period. Serum B-type natriuretic peptide concentration was measured without a 24-hour period prior to the surgical procedure and the value obtained was correlated with a short-term all-cause mortality.Results:
Data analysis showed that all-cause mortality rates were equal to 9.5% in 30 days. Accuracy analysis by the receiver operating characteristic curve found an ideal cut-off value of B-type natriuretic peptide equal to 150 pg/mL in relation to mortality (AUC=0.82, 95% CI=0.71-0.87, P<0.001). Multivariate analysis showed that B-type natriuretic peptide value greater than or equal to 150 pg/mL (P=0.030, HR=3.99, 95% CI=1.14-13.98) was an independent predictor of all-cause mortality in a 30-day follow-up period.Conclusion:
Preoperative serum B-type natriuretic peptide concentration is an independent predictor of short-term all-cause mortality in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass.Palabras clave
Texto completo:
1
Base de datos:
LILACS
Asunto principal:
Puente de Arteria Coronaria
/
Péptido Natriurético Encefálico
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
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Humans
/
Male
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Rev. bras. cir. cardiovasc
Asunto de la revista:
CARDIOLOGIA
/
CIRURGIA GERAL
Año:
2017
Tipo del documento:
Article
País de afiliación:
Brasil