Isolated pericardial effusion and transient abnormal myelopoiesis in a fetus with Down's syndrome.
J Obstet Gynaecol Res
; 26(4): 303-6, 2000 Aug.
Article
en En
| MEDLINE
| ID: mdl-11049242
ABSTRACT
Isolated pericardial effusion was detected in a fetus at 34 weeks of gestation. A male infant weighing 2,044 g was born by cesarean section because of a non-assuring fetal heart rate pattern at 35 weeks of gestation. Transient leukocytosis (36,100/microl) with 49% blast cells was seen in this neonate. The infant's karyotype was 47, XY + 21. The pericardial effusion disappeared after treatment with prednisolone at a dose of 2 mg/kg/day. Hypothyroidism was subsequently found. Thus, the subject patient with Down's syndrome developed isolated pericardial effusion, transient abnormal myelopoiesis (TAM), and hypothyroidism. Because more than 20% of the infants with TAM and Down's syndrome develop acute nonlymphocytic leukemia in early childhood, he is being closely observed.
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Base de datos:
MEDLINE
Asunto principal:
Derrame Pericárdico
/
Síndrome de Down
/
Leucopoyesis
/
Enfermedades Fetales
/
Hipotiroidismo
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
J Obstet Gynaecol Res
Asunto de la revista:
GINECOLOGIA
/
OBSTETRICIA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Japón