Disposition of olanzapine in Chinese schizophrenic patients.
Int J Clin Pharmacol Ther
; 38(10): 482-5, 2000 Oct.
Article
en En
| MEDLINE
| ID: mdl-11073289
ABSTRACT
The disposition of olanzapine was evaluated in 21 male chronic schizophrenic patients. A single 10 mg dose of olanzapine was administered and blood sampling performed over the following 120 hours. The mean (+/- SD) oral clearance and elimination half-life of olanzapine were 51.5+/-61.6 l/h and 30.9+/-4.3 hours, respectively. A wide interpatient variability was found. Compared to the population norms, no significant differences were observed between different populations and Chinese patients in olanzapine disposition.
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Base de datos:
MEDLINE
Asunto principal:
Esquizofrenia
/
Pirenzepina
Límite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Int J Clin Pharmacol Ther
Asunto de la revista:
FARMACOLOGIA
/
TERAPIA POR MEDICAMENTOS
Año:
2000
Tipo del documento:
Article
País de afiliación:
Taiwán