[Benzodiazepines and pregnancy]. / Benzodiazépines et grossesse.
Therapie
; 55(5): 587-95, 2000.
Article
en Fr
| MEDLINE
| ID: mdl-11201973
ABSTRACT
The use of benzodiazepines is not negligible in pregnant woman and self-medication is considerable. To investigate the effects on the fetus of benzodiazepines used during pregnancy, we reviewed animal and clinical studies completed with observations of CRPV (Centres Régionaux de Pharmacovigilance). Pooled results indicate that the risk of malformations associated with first-trimester exposure to benzodiazepines remains small. However, in a fetus exposed essentially to long-acting benzodiazepines on a long-term basis, neonatal hypotonicity, failure to feed and/or withdrawal syndrom could be observed.
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Base de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Anomalías Inducidas por Medicamentos
/
Benzodiazepinas
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
País/Región como asunto:
Europa
Idioma:
Fr
Revista:
Therapie
Año:
2000
Tipo del documento:
Article
País de afiliación:
Francia