Membrane fluidity correlates with liver cancer cell proliferation and infiltration potential.

Funaki, N O; Tanaka, J; Kohmoto, M; Sugiyama, T; Ohshio, G; Nonaka, A; Yotsumoto, F; Takeda, Y; Imamura, M

Funaki, N O; Tanaka, J; Kohmoto, M; Sugiyama, T; Ohshio, G; Nonaka, A; Yotsumoto, F; Takeda, Y; Imamura, M.

Afiliación

Funaki NO; Department of Surgery, Shiga Medical Center for Adults, Moriyama City, Japan.

Oncol Rep ; 8(3): 527-32, 2001.

Article en En | MEDLINE | ID: mdl-11295074

ABSTRACT

ABSTRACT

We developed a method to measure membrane fluidity of living cancer cells in two- and three-dimensional cultures, and found that there was a close relationship between the membrane fluidity of cancer cells and their proliferative and infiltrative ability. Membrane fluidity is thus a promising indicator of the probability of cancer recurrence.

Asunto(s)

Carcinoma Hepatocelular/patología; Membrana Celular/fisiología; Neoplasias Hepáticas/patología; Fluidez de la Membrana; Bromodesoxiuridina; División Celular; Polarización de Fluorescencia; Humanos; Microscopía de Contraste de Fase; Modelos Biológicos; Células Tumorales Cultivadas

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Base de datos: MEDLINE Asunto principal: Membrana Celular / Carcinoma Hepatocelular / Neoplasias Hepáticas / Fluidez de la Membrana Límite: Humans Idioma: En Revista: Oncol Rep Asunto de la revista: NEOPLASIAS Año: 2001 Tipo del documento: Article País de afiliación: Japón

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