Applying Bradford Hill's criteria for causation to neuropsychiatry: challenges and opportunities.
J Neuropsychiatry Clin Neurosci
; 13(3): 318-25, 2001.
Article
en En
| MEDLINE
| ID: mdl-11514637
ABSTRACT
Establishing an argument of causation is an important research activity with major clinical and scientific implications. Sir Austin Bradford Hill proposed criteria to establish such an argument. These criteria include the strength of the association, consistency, specificity, temporal sequence, biological gradient, biologic rationale, coherence, experimental evidence, and analogous evidence. These criteria are reviewed with the goal of facilitating an increase in rigor for establishing arguments of causation in neuropsychiatry. The challenges and opportunities related to these criteria in neuropsychiatry are reviewed, as are two important arguments for causation one for poststroke depression and one for brain injury as a cause of psychiatric disorders.
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Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Medicina Basada en la Evidencia
/
Trastornos Mentales
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
J Neuropsychiatry Clin Neurosci
Asunto de la revista:
NEUROLOGIA
/
PSIQUIATRIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Canadá