Some evidence for the maturity of peripheral adrenergic nerves in new-born guinea-pigs.
Aust J Exp Biol Med Sci
; 53(3): 215-22, 1975 Jun.
Article
en En
| MEDLINE
| ID: mdl-1191135
ABSTRACT
The fluorescence histochemical technique of Falck and Hillarp revealed a similar distribution and density of peripheral adrenergic nerves in new-born and adult guinea-pigs. The accumulation of tritiated noradrenaline by tracheae from new-born guinea-pigs, assumed to be uptake into adrenergic nerves, was not less than the accumulation by tracheae from adult animals. There was equal potentiation by cocaine (1 x 10(-5)M) of responses to noradrenaline on tracheal chain preparations taken from new-born and adult guinea-pigs. The evidence supports the hypothesis that the guinea-pig has a functional, well differentiated peripheral adrenergic nervous system at birth. This would account for the apparent inability to produce a long-lasting sympathectomy by administration of 6-hydroxydopamine to new-born guinea-pigs.
Buscar en Google
Base de datos:
MEDLINE
Asunto principal:
Nervios Periféricos
/
Sistema Nervioso Simpático
/
Cobayas
/
Animales Recién Nacidos
Límite:
Animals
Idioma:
En
Revista:
Aust J Exp Biol Med Sci
Año:
1975
Tipo del documento:
Article