Outcome of IgM- and IgG-seropositive cases of varicella zoster in pregnancy.

OBJECTIVE: To study the outcome of IgG- and IgM-seropositive cases of varicella zoster virus (VZV) in pregnancy. STUDY DESIGN: The VZV immune status of 120 pregnant women who had been exposed to VZV and did not recall a history of VZV infection was determined, and 109 were VZV immune. Eleven women were both IgG and IgM seropositive, and the outcomes of their pregnancies were studied. RESULTS: Nine of the 11 VZV IgM-, IgG-seropositive pregnant women were asymptomatic, without fetal damage. CONCLUSION: The majority of the women were asymptomatic, but no statement about the relative risk of being affected by the virus can be made.