Estimating the burden of disease attributable to iron deficiency anaemia in South Africa in 2000.
S Afr Med J
; 97(8 Pt 2): 741-6, 2007 Aug.
Article
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| MEDLINE
| ID: mdl-17952232
OBJECTIVES: To estimate the extent of iron deficiency anaemia (IDA) among children aged 0 - 4 years and pregnant women aged 15 - 49 years, and the burden of disease attributed to IDA in South Africa in 2000. DESIGN: The comparative risk assessment (CRA) methodology of the World Health Organization (WHO) was followed using local prevalence and burden estimates. IDA prevalence came from re-analysis of the South African Vitamin A Consultative Group study in the case of the children, and from a pooled estimate from several studies in the case of the pregnant women (haemoglobin level < 11 g/dl and ferritin level < 12 microg/l). Monte Carlo simulation-modelling was used for the uncertainty analysis. SETTING: South Africa. SUBJECTS: Children under 5 years and pregnant women 15 - 49 years. OUTCOME MEASURES: Direct sequelae of IDA, maternal and perinatal deaths and disability-adjusted life years (DALYs) from mild mental disability related to IDA. Results. It is estimated that 5.1% of children and 9 - 12% of pregnant women had IDA and that about 7.3% of perinatal deaths and 4.9% of maternal deaths were attributed to IDA in 2000. Overall, about 174,976 (95% uncertainty interval 150,344 - 203,961) healthy years of life lost (YLLs), or between 0.9% and 1.3% of all DALYs in South Africa in 2000, were attributable to IDA. CONCLUSIONS: This first study in South Africa to quantify the burden from IDA suggests that it is a less serious public health problem in South Africa than in many other developing countries. Nevertheless, this burden is preventable, and the study highlights the need to disseminate the food-based dietary guidelines formulated by the National Department of Health to people who need them and to monitor the impact of the food fortification programme.
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Base de datos:
MEDLINE
Asunto principal:
Complicaciones Hematológicas del Embarazo
/
Costo de Enfermedad
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Anemia Ferropénica
Tipo de estudio:
Etiology_studies
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Prevalence_studies
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Risk_factors_studies
Límite:
Adolescent
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Adult
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Child, preschool
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Female
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Humans
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Infant
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Middle aged
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Pregnancy
País/Región como asunto:
Africa
Idioma:
En
Revista:
S Afr Med J
Año:
2007
Tipo del documento:
Article