2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: optimization via array synthesis.
Bioorg Med Chem Lett
; 18(8): 2640-4, 2008 Apr 15.
Article
en En
| MEDLINE
| ID: mdl-18374566
2-Arylbenzoxazole 5 was identified as a hit from a fluorescence-based high-throughput screen for CETP inhibitors. The synthesis and SAR investigation employing array synthesis of the A- and B-rings are described.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Benzoxazoles
/
Proteínas de Transferencia de Ésteres de Colesterol
Límite:
Humans
Idioma:
En
Revista:
Bioorg Med Chem Lett
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos