Plasticity in the adult brain: lessons from the visual system.
Exp Brain Res
; 192(3): 335-41, 2009 Jan.
Article
en En
| MEDLINE
| ID: mdl-18668231
ABSTRACT
While cortical circuits display maximal sensitivity to sensory experience during critical periods of early postnatal development, far less plasticity is present in the mature brain. Ocular dominance shift of visual cortical neurons in response to eye occlusion and recovery of visual functions from a period of sensory deprivation are two classical models in the study of critical period determinants in the visual cortex. Recent papers employing various pharmacological and environmental strategies have shown that it is possible to reinstate much greater levels of plasticity in the adult visual cortex than previously suspected. These studies point toward intracortical inhibition as a crucial determinant for critical period regulation in the visual system and have a great potential for therapeutic rehabilitation and recovery from injury in the adult brain.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Corteza Visual
/
Vías Visuales
/
Encéfalo
/
Neurogénesis
/
Plasticidad Neuronal
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Exp Brain Res
Año:
2009
Tipo del documento:
Article
País de afiliación:
Italia