Evaluation of ocular manifestations and blindness in HIV/AIDS patients on HAART in a tertiary care hospital in western India.
Br J Ophthalmol
; 93(1): 88-90, 2009 Jan.
Article
en En
| MEDLINE
| ID: mdl-18952644
ABSTRACT
BACKGROUND:
HIV has various ocular manifestations and with the widespread introduction of highly active antiretroviral therapy (HAART), their pattern and prevalence is expected to change. Therefore, we evaluated the HIV/AIDS patients on HAART for ocular manifestations and blindness.METHODS:
In this cross-sectional study, 112 HIV-positive patients on HAART presenting to the HIV clinic with CD4 countRESULTS:
The prevalence of ocular manifestations in HIV/AIDS patients on HAART was 8% (nine out of 112). Seven (6%) of the patients had visual impairment including one patient with blindness. The ocular manifestations included HIV retinopathy (5%), immune recovery uveitis (3%), immune recovery vitritis (3%) and Cytomegalovirus retinitis (2%). The prevalence of ocular manifestations and visual impairment was higher with the CD4 count of 0-100 cells/microl (p = 0.002). The prevalence of ocular manifestations was also higher in patients with WHO clinical stages 3 and 4 (p = 0.017).CONCLUSIONS:
HAART may be the cause for decline in the prevalence of ocular diseases and visual impairment in HIV/AIDS patients. CD4 count and WHO clinical stage may help predict their occurrence.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Retina
/
Infecciones Virales del Ojo
/
Infecciones por VIH
/
Ceguera
/
VIH-1
/
Terapia Antirretroviral Altamente Activa
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Br J Ophthalmol
Año:
2009
Tipo del documento:
Article
País de afiliación:
India