Hippophae rhamnoides L. and dexpanthenol-bepanthene on blood flow after experimental skin burns in rats using 133Xe clearance technique.
Hell J Nucl Med
; 12(1): 55-8, 2009.
Article
en En
| MEDLINE
| ID: mdl-19330185
ABSTRACT
UNLABELLED The aim of the present experimental study was to determine and compare the effect of Hippophae rhamnoides L. extract (HRe-1) and of dexpanthenol on the blood flow of a wound region, in rats using xenon-133 ((133)Xe) clearance technique. METHODS:
Burn wounds were made on both thighs of rats and, HRe-1 and dexpanthenol were applied topically on the wound region only in the right thigh for a period of 8 days. The effect of HRe-1 and of dexpanthenol on blood flow of the wound region was assessed before and after their topical application by using the (133)Xe clearance technique.RESULTS:
HRe-1 increased significantly blood flow of the wound region (P<0.05). Dexpanthenol showed a smaller increase in blood flow. In conclusion, our results in rats suggest that HRe-1 increases blood flow of the wound area and can be used for the treatment of skin wound healing, preferably than dexpanthenol.
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Base de datos:
MEDLINE
Asunto principal:
Ácido Pantoténico
/
Piel
/
Radioisótopos de Xenón
/
Quemaduras
/
Extractos Vegetales
/
Hippophae
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Hell J Nucl Med
Asunto de la revista:
MEDICINA NUCLEAR
Año:
2009
Tipo del documento:
Article
País de afiliación:
Turquía