Bleeding in acute promyelocytic leukemia (APL): fibrinolysis or defibrination?
Nouv Rev Fr Hematol (1978)
; 33(1): 39-41, 1991.
Article
en En
| MEDLINE
| ID: mdl-1945823
ABSTRACT
The coagulation abnormalities in 20 cases of acute promyelocytic leukemia (APL) treated at a single institution were reviewed. A remarkably uniform picture of defibrination and increased FDPs with well-preserved levels of other coagulation factors including AT-III was seen. Our data, together with those available in the literature, do not support DIC as the underlying mechanism of bleeding but seem rather to point to increased proteolysis as the cause.
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Base de datos:
MEDLINE
Asunto principal:
Trastornos de la Coagulación Sanguínea
/
Fibrina
/
Leucemia Promielocítica Aguda
/
Fibrinólisis
/
Hemorragia
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Nouv Rev Fr Hematol (1978)
Año:
1991
Tipo del documento:
Article
País de afiliación:
España