Stereoselective radical addition of an acetal to sterically tuned enantiomerically pure N-sulfinyl imines.
Chem Pharm Bull (Tokyo)
; 58(2): 265-9, 2010 Feb.
Article
en En
| MEDLINE
| ID: mdl-20118594
ABSTRACT
Enantiomerically enriched sulfonamides were synthesized by the radical addition of an acetal to enantiomerically pure N-sulfinyl imines using dimethylzinc-air and boron trifluoride diethyl etherate. Higher levels of stereocontrol were observed by using a mesitylenesulfinyl group. Furthermore, an amine and an amino alcohol with high enantiomeric purity were obtainable from the sulfonamide product.
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Base de datos:
MEDLINE
Asunto principal:
Sulfonamidas
/
Iminas
/
Acetales
Idioma:
En
Revista:
Chem Pharm Bull (Tokyo)
Año:
2010
Tipo del documento:
Article
País de afiliación:
Japón