Neonatal herpes simplex virus.
J Matern Fetal Neonatal Med
; 24 Suppl 1: 88-90, 2011 Oct.
Article
en En
| MEDLINE
| ID: mdl-21942600
ABSTRACT
Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in utero, the transmission frequently occurs during delivery. The disease may be disseminated, localized to the central nervous system, or involving skin, eye and/or mouth. Mortality rates markedly decreased with high-dose antiviral treatment. Diagnosis of neonatal infection is based on viral isolation from ulcerated vesicles or by scarifying mucocutaneous lesions. Recently polymerase chain reaction plays a central role for both viral detection (skin, mucosal, cerebrospinal fluid samples) and response to therapy. Vertical transmission may be decreased by prophylactic antiviral treatment.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Simplexvirus
/
Herpes Simple
/
Enfermedades del Recién Nacido
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Asunto de la revista:
OBSTETRICIA
/
PERINATOLOGIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Italia