Appraisal of the porcine kidney autotransplantation model.
Front Biosci (Elite Ed)
; 4(4): 1345-57, 2012 01 01.
Article
en En
| MEDLINE
| ID: mdl-22201959
ABSTRACT
Animal models are extensively used for transplantation related research, especially kidney transplantation. Porcine autotransplantation models are considered to be favorable regarding translatability to the human setting. The key determinants for translatability of the model are discussed, comprising animal age, development, anatomy, anesthesia and surgical protocols, and perioperative care. With the detailed discussion of these determinants and the pitfalls in diagnosing animal discomfort, an attempt is made to provide a uniform porcine kidney autotransplantation model with tools to improve currently used models.
Buscar en Google
Base de datos:
MEDLINE
Asunto principal:
Trasplante de Riñón
/
Modelos Animales de Enfermedad
Tipo de estudio:
Guideline
/
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Front Biosci (Elite Ed)
Asunto de la revista:
BIOLOGIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Países Bajos