Minocycline as potent anticonvulsant in a patient with astrocytoma and drug resistant epilepsy.
Seizure
; 21(3): 227-8, 2012 Apr.
Article
en En
| MEDLINE
| ID: mdl-22265576
ABSTRACT
Minocycline, a tetracycline family antibiotic, is known to inhibit microglial activation and proinflammatory cytokine release in animal models. Experimental data show that these immune processes may play a role in epilepto- and ictogenesis. We present the case of a patient with marked reduction in seizure frequency during minocycline therapy with severe symptomatic epilepsy due to an astrocytoma.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Astrocitoma
/
Neoplasias Encefálicas
/
Epilepsia
/
Minociclina
/
Anticonvulsivantes
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Seizure
Asunto de la revista:
NEUROLOGIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Alemania