Daytime secretion of salivary cortisol and alpha-amylase in preschool-aged children with autism and typically developing children.
J Autism Dev Disord
; 42(12): 2648-58, 2012 Dec.
Article
en En
| MEDLINE
| ID: mdl-22477468
ABSTRACT
We examined daytime salivary cortisol and salivary alpha-amylase (sAA) secretion levels and variability in preschool-aged children with autism (AUT) and typically developing children (TYP). Fifty-two subjects (26 AUT and 26 TYP) were enrolled. Salivary samples were obtained at waking, midday, and bedtime on two consecutive days at three phases (baseline, 3 months later, 6 months later). There were modest increases in waking cortisol and sAA levels in AUT relative to TYP, but the increases were not statistically significant. Important differences were observed in cortisol and sAA variability between AUT and TYP. There was also a graded response among AUT by functional status--cortisol and sAA secretion levels were higher when IQ was lower.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Saliva
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Trastorno Autístico
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Hidrocortisona
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Ritmo Circadiano
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Alfa-Amilasas Salivales
Límite:
Child, preschool
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Female
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Humans
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Male
Idioma:
En
Revista:
J Autism Dev Disord
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos