[Primitive neuroectodermal tumor of the testis. Molecular analysis and discussion of genesis]. / Primitiver neuroektodermaler Tumor im Hoden. Molekulare Analyse und Diskussion der Entstehung.
Pathologe
; 34(1): 70-3, 2013 Feb.
Article
en De
| MEDLINE
| ID: mdl-22706883
ABSTRACT
We describe a case of a testicular primitive neuroectodermal tumor (PNET) with intratubular germ cell neoplasia of the adjacent testicular parenchyma. The occurrence of testicular PNET is rare because malignant transformation of testicular germ cell tumors into somatic malignancy is uncommon. Based on morphological, immunohistochemical and molecular pathological findings these tumors resemble central PNETs as they otherwise typically occur in children without rearrangement of the Ewing sarcoma breakpoint region (EWSR) gene on chromosome 22. This case also showed no evidence for a translocation.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Testiculares
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Biomarcadores de Tumor
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Transformación Celular Neoplásica
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Neoplasias de Células Germinales y Embrionarias
Límite:
Adult
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Humans
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Male
Idioma:
De
Revista:
Pathologe
Año:
2013
Tipo del documento:
Article