[Adipokines in healthy and obese children]. / Adipoquinas en el niño sano y con obesidad.
An Pediatr (Barc)
; 78(3): 189.e1-189.e15, 2013 Mar.
Article
en Es
| MEDLINE
| ID: mdl-23228441
ABSTRACT
The worldwide increase in the prevalence of obesity in children and adolescents during the last decades, as well as the mounting evidence indicating that obesity is associated with an increased incidence of comorbidities and the risk of premature death, resulting in a high economic impact, has stimulated obesity focused research. These studies have highlighted the prominent endocrine activity of adipose tissue, which is exerted through the synthesis and secretion of a wide variety of peptides and cytokines, called adipokines. This review presents a summary of the current knowledge and most relevant studies of adipokine dynamics and actions in children, focusing on the control of energy homeostasis, metabolic regulation (particularly carbohydrate metabolism), and inflammation. The particularities of adipose secretion and actions in healthy children, from birth to adolescence, and the modifications induced by early onset obesity are highlighted.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Adipoquinas
/
Obesidad
Tipo de estudio:
Risk_factors_studies
Límite:
Child
/
Humans
Idioma:
Es
Revista:
An Pediatr (Barc)
Asunto de la revista:
PEDIATRIA
Año:
2013
Tipo del documento:
Article