Purpura fulminans associated with Streptococcus pneumoniae septicemia in an asplenic pediatric patient.
Actas Dermosifiliogr
; 104(7): 623-7, 2013 Sep.
Article
en En
| MEDLINE
| ID: mdl-23985086
Purpura fulminans is a rapidly progressive syndrome of small-vessel thrombosis and hemorrhagic necrosis of the skin accompanied by disseminated intravascular coagulation. We describe a case of Streptococcus pneumoniae septicemia in an asplenic 5-year-old boy on oral tacrolimus, with a past medical history of multivisceral organ transplantation and subsequent development of purpura fulminans on his chest and distal extremities. The acute infectious form of purpura fulminans is usually caused by gram-negative bacteria. Cases secondary to gram-positive encapsulated bacteria usually occur when individuals are immuno-suppressed or have anatomic or functional asplenia. Our patient had both, which likely increased his susceptibility, and he responded well to antimicrobial therapy in addition to prophylactic coverage in the setting of his immunosuppression. We review the literature for similar cases due to S. pneumoniae in the pediatric population and discuss the etiology and treatment of purpura fulminans.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Complicaciones Posoperatorias
/
Infecciones Estreptocócicas
/
Streptococcus pneumoniae
/
Bacteriemia
/
Púrpura Fulminante
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Child, preschool
/
Humans
/
Male
Idioma:
En
Revista:
Actas Dermosifiliogr
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos