Basic research: Salt wasting in distal renal tubular acidosis-new look, old problem.
Nat Rev Nephrol
; 9(12): 712-3, 2013 Dec.
Article
en En
| MEDLINE
| ID: mdl-24189652
ABSTRACT
Acidosis affects sodium and potassium excretion, likely via the pH sensitivity of ion transporters. A recent paper shows that ß-intercalated cells with deleted H(+)-ATPase release ATP into urine, which induces the production of prostaglandin E2 (PGE2). PGE2 then reduces sodium absorption in the principal cells of the cortical collecting tubule and increases potassium secretion.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Equilibrio Hidroelectrolítico
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Sodio en la Dieta
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Potasio en la Dieta
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Túbulos Renales Colectores
Límite:
Animals
Idioma:
En
Revista:
Nat Rev Nephrol
Asunto de la revista:
NEFROLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos